ID   ALLC_PSEAB              Reviewed;         332 AA.
AC   Q02JZ8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Probable allantoicase {ECO:0000255|HAMAP-Rule:MF_00813};
DE            EC=3.5.3.4 {ECO:0000255|HAMAP-Rule:MF_00813};
DE   AltName: Full=Allantoate amidinohydrolase {ECO:0000255|HAMAP-Rule:MF_00813};
GN   Name=alc {ECO:0000255|HAMAP-Rule:MF_00813}; OrderedLocusNames=PA14_44850;
OS   Pseudomonas aeruginosa (strain UCBPP-PA14).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCBPP-PA14;
RX   PubMed=17038190; DOI=10.1186/gb-2006-7-10-r90;
RA   Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S.,
RA   Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L., Grills G.,
RA   Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.;
RT   "Genomic analysis reveals that Pseudomonas aeruginosa virulence is
RT   combinatorial.";
RL   Genome Biol. 7:R90.1-R90.14(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=allantoate + H2O = (S)-ureidoglycolate + urea;
CC         Xref=Rhea:RHEA:11016, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:17536, ChEBI:CHEBI:57296; EC=3.5.3.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00813};
CC   -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation; (S)-
CC       ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00813}.
CC   -!- SIMILARITY: Belongs to the allantoicase family. {ECO:0000255|HAMAP-
CC       Rule:MF_00813}.
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DR   EMBL; CP000438; ABJ10695.1; -; Genomic_DNA.
DR   RefSeq; WP_003110786.1; NZ_CP034244.1.
DR   AlphaFoldDB; Q02JZ8; -.
DR   SMR; Q02JZ8; -.
DR   EnsemblBacteria; ABJ10695; ABJ10695; PA14_44850.
DR   KEGG; pau:PA14_44850; -.
DR   HOGENOM; CLU_038797_1_2_6; -.
DR   OMA; MDDGWET; -.
DR   BioCyc; PAER208963:G1G74-3768-MON; -.
DR   UniPathway; UPA00395; UER00654.
DR   Proteomes; UP000000653; Chromosome.
DR   GO; GO:0004037; F:allantoicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000256; P:allantoin catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00813; Allantoicase; 1.
DR   InterPro; IPR005164; Allantoicase.
DR   InterPro; IPR015908; Allantoicase_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   PANTHER; PTHR12045; PTHR12045; 1.
DR   Pfam; PF03561; Allantoicase; 2.
DR   PIRSF; PIRSF016516; Allantoicase; 1.
DR   SUPFAM; SSF49785; SSF49785; 2.
DR   TIGRFAMs; TIGR02961; allantoicase; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Purine metabolism.
FT   CHAIN           1..332
FT                   /note="Probable allantoicase"
FT                   /id="PRO_1000062284"
SQ   SEQUENCE   332 AA;  36771 MW;  67154A45F463D98F CRC64;
     MNAKHAPFRH YLDLADARLG SQVVAVSDEW FAPASRMLQA GEPVWKEGVF DDSGKWMDGW
     ETRRKRFEGH DQAVIRLGVP GVLKGVDIDT RFFTGNHPPA ASLDGCFCTE GDPDDSTSWS
     EVLPAVGLQG DSHHYHPIDD ERPWTHLRLN IYPDGGIARL RLYGVPYRDW SSLPPGTALD
     LAAAVNGGRA LACSDQHFGR MGNLLNPGRA INMGDGWETG RRRTPGHDWV IVALGHPGSI
     EAAVVDTLHF KGNYPESCSI QAAFVEGGNE ARIEAQSLFW RELLPAQKLE MHQEHRFERH
     LNALGPITHV RLNIFPDGGV SRLRLFGSPQ LP