ALLC_PSEAE
ID ALLC_PSEAE Reviewed; 332 AA.
AC Q9I3J8;
DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Probable allantoicase {ECO:0000255|HAMAP-Rule:MF_00813};
DE EC=3.5.3.4 {ECO:0000255|HAMAP-Rule:MF_00813};
DE AltName: Full=Allantoate amidinohydrolase {ECO:0000255|HAMAP-Rule:MF_00813};
GN Name=alc {ECO:0000255|HAMAP-Rule:MF_00813}; OrderedLocusNames=PA1515;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=allantoate + H2O = (S)-ureidoglycolate + urea;
CC Xref=Rhea:RHEA:11016, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199,
CC ChEBI:CHEBI:17536, ChEBI:CHEBI:57296; EC=3.5.3.4;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00813};
CC -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation; (S)-
CC ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.
CC {ECO:0000255|HAMAP-Rule:MF_00813}.
CC -!- SIMILARITY: Belongs to the allantoicase family. {ECO:0000255|HAMAP-
CC Rule:MF_00813}.
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DR EMBL; AE004091; AAG04904.1; -; Genomic_DNA.
DR PIR; F83455; F83455.
DR RefSeq; NP_250206.1; NC_002516.2.
DR RefSeq; WP_003114681.1; NZ_QZGE01000032.1.
DR AlphaFoldDB; Q9I3J8; -.
DR SMR; Q9I3J8; -.
DR STRING; 287.DR97_507; -.
DR PaxDb; Q9I3J8; -.
DR PRIDE; Q9I3J8; -.
DR DNASU; 883130; -.
DR EnsemblBacteria; AAG04904; AAG04904; PA1515.
DR GeneID; 883130; -.
DR KEGG; pae:PA1515; -.
DR PATRIC; fig|208964.12.peg.1567; -.
DR PseudoCAP; PA1515; -.
DR HOGENOM; CLU_038797_1_2_6; -.
DR InParanoid; Q9I3J8; -.
DR OMA; MDDGWET; -.
DR PhylomeDB; Q9I3J8; -.
DR BioCyc; PAER208964:G1FZ6-1542-MON; -.
DR UniPathway; UPA00395; UER00654.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0004037; F:allantoicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0000256; P:allantoin catabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR HAMAP; MF_00813; Allantoicase; 1.
DR InterPro; IPR005164; Allantoicase.
DR InterPro; IPR015908; Allantoicase_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR12045; PTHR12045; 1.
DR Pfam; PF03561; Allantoicase; 2.
DR PIRSF; PIRSF016516; Allantoicase; 1.
DR SUPFAM; SSF49785; SSF49785; 2.
DR TIGRFAMs; TIGR02961; allantoicase; 1.
PE 3: Inferred from homology;
KW Hydrolase; Purine metabolism; Reference proteome.
FT CHAIN 1..332
FT /note="Probable allantoicase"
FT /id="PRO_0000205923"
SQ SEQUENCE 332 AA; 36843 MW; 1322D7A1F6CEB03B CRC64;
MNAEHSPFRH YLDLADARLG SQVVAVSDEW FAPASRMLQA GEPVWKEGVF DDSGKWMDGW
ETRRKRFEGH DQAVIRLGVP GVLKGVDIDT RFFTGNHPPA ASLDGCFCAE GDPDDSTSWS
EVLAAVGLQG DSHHYHPIDD ERPWTHLRLN IYPDGGIARL RLYGVPYRDW SNQPPGTALD
LAAAVNGGRA LACSDQHFGR MGNLLNPGRA INMGDGWETG RRRTPGHDWV IVALGHPGSI
EAAVVDTLHF KGNYPESCSI QAAFVEGGNE ARIEAQSLFW RELLPAQKLE MHQEHRFERH
LNALGPITHV RLNIFPDGGV SRLRLFGRPQ LP
