ALLC_RALSO
ID ALLC_RALSO Reviewed; 336 AA.
AC Q8XUB7;
DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=Probable allantoicase {ECO:0000255|HAMAP-Rule:MF_00813};
DE EC=3.5.3.4 {ECO:0000255|HAMAP-Rule:MF_00813};
DE AltName: Full=Allantoate amidinohydrolase {ECO:0000255|HAMAP-Rule:MF_00813};
GN Name=alc {ECO:0000255|HAMAP-Rule:MF_00813}; OrderedLocusNames=RSc3274;
GN ORFNames=RS02503;
OS Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=267608;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GMI1000;
RX PubMed=11823852; DOI=10.1038/415497a;
RA Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL Nature 415:497-502(2002).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=allantoate + H2O = (S)-ureidoglycolate + urea;
CC Xref=Rhea:RHEA:11016, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199,
CC ChEBI:CHEBI:17536, ChEBI:CHEBI:57296; EC=3.5.3.4;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00813};
CC -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation; (S)-
CC ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.
CC {ECO:0000255|HAMAP-Rule:MF_00813}.
CC -!- SIMILARITY: Belongs to the allantoicase family. {ECO:0000255|HAMAP-
CC Rule:MF_00813}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL646052; CAD17062.1; -; Genomic_DNA.
DR RefSeq; WP_011003159.1; NC_003295.1.
DR AlphaFoldDB; Q8XUB7; -.
DR SMR; Q8XUB7; -.
DR STRING; 267608.RSc3274; -.
DR EnsemblBacteria; CAD17062; CAD17062; RSc3274.
DR GeneID; 60502786; -.
DR KEGG; rso:RSc3274; -.
DR eggNOG; COG4266; Bacteria.
DR HOGENOM; CLU_038797_1_2_4; -.
DR OMA; MDDGWET; -.
DR UniPathway; UPA00395; UER00654.
DR Proteomes; UP000001436; Chromosome.
DR GO; GO:0004037; F:allantoicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0000256; P:allantoin catabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR HAMAP; MF_00813; Allantoicase; 1.
DR InterPro; IPR005164; Allantoicase.
DR InterPro; IPR015908; Allantoicase_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR12045; PTHR12045; 1.
DR Pfam; PF03561; Allantoicase; 2.
DR PIRSF; PIRSF016516; Allantoicase; 1.
DR SUPFAM; SSF49785; SSF49785; 2.
DR TIGRFAMs; TIGR02961; allantoicase; 1.
PE 3: Inferred from homology;
KW Hydrolase; Purine metabolism; Reference proteome.
FT CHAIN 1..336
FT /note="Probable allantoicase"
FT /id="PRO_0000205926"
SQ SEQUENCE 336 AA; 37594 MW; 8429E9424173319E CRC64;
MAMPTLDPNA PDFTRRYPNL ADPRLGAVAT FATDEFFAPK DRMLNPEPAV FIPGKYDDHG
KWMDGWETRR RRNGGYDHCI VKLARPGVVK GVDIDTSHFT GNFPPAASID AAYLPHGEPT
DATQWTEIVP STTLQGNSHH YLDVFGTHAY THLRVNIYPD GGIARLRVYG QPQVDWKGAD
RATLFDLAAM ENGAYVVEVN NQHFGLASSL LMPGRGINMG DGWETRRRRE PGNDWCIIAL
AHPGRIRKIE VDTAHFKGNF ADRVSLQAAR VTGGTDATLK TQAMFWQTLL PEQKLQMDHQ
HYYEAELADL GPVTHVRFNM FPDGGVSRLR LWGALE