ID   ALLC_SCHPO              Reviewed;         342 AA.
AC   Q09913;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 132.
DE   RecName: Full=Probable allantoicase;
DE            EC=3.5.3.4;
DE   AltName: Full=Allantoate amidinohydrolase;
GN   ORFNames=SPAC1F7.09c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Utilization of purines as secondary nitrogen sources, when
CC       primary sources are limiting.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=allantoate + H2O = (S)-ureidoglycolate + urea;
CC         Xref=Rhea:RHEA:11016, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:17536, ChEBI:CHEBI:57296; EC=3.5.3.4;
CC   -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation; (S)-
CC       ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.
CC   -!- SIMILARITY: Belongs to the allantoicase family. {ECO:0000305}.
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DR   EMBL; CU329670; CAA91956.1; -; Genomic_DNA.
DR   PIR; S62581; S62581.
DR   RefSeq; NP_594495.1; NM_001019924.2.
DR   AlphaFoldDB; Q09913; -.
DR   SMR; Q09913; -.
DR   BioGRID; 277946; 6.
DR   STRING; 4896.SPAC1F7.09c.1; -.
DR   MaxQB; Q09913; -.
DR   PaxDb; Q09913; -.
DR   EnsemblFungi; SPAC1F7.09c.1; SPAC1F7.09c.1:pep; SPAC1F7.09c.
DR   GeneID; 2541441; -.
DR   KEGG; spo:SPAC1F7.09c; -.
DR   PomBase; SPAC1F7.09c; -.
DR   VEuPathDB; FungiDB:SPAC1F7.09c; -.
DR   eggNOG; KOG4145; Eukaryota.
DR   HOGENOM; CLU_038797_0_0_1; -.
DR   InParanoid; Q09913; -.
DR   OMA; MDDGWET; -.
DR   PhylomeDB; Q09913; -.
DR   UniPathway; UPA00395; UER00654.
DR   PRO; PR:Q09913; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0004037; F:allantoicase activity; EXP:PomBase.
DR   GO; GO:0000256; P:allantoin catabolic process; ISO:PomBase.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0000050; P:urea cycle; IC:PomBase.
DR   HAMAP; MF_00813; Allantoicase; 1.
DR   InterPro; IPR005164; Allantoicase.
DR   InterPro; IPR015908; Allantoicase_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   PANTHER; PTHR12045; PTHR12045; 1.
DR   Pfam; PF03561; Allantoicase; 2.
DR   PIRSF; PIRSF016516; Allantoicase; 1.
DR   SUPFAM; SSF49785; SSF49785; 2.
DR   TIGRFAMs; TIGR02961; allantoicase; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Purine metabolism; Reference proteome.
FT   CHAIN           1..342
FT                   /note="Probable allantoicase"
FT                   /id="PRO_0000205913"
SQ   SEQUENCE   342 AA;  37965 MW;  313807C60C41E700 CRC64;
     MSVENVERLS PEQADAFFGQ SSVDLISRAL GGQVLGCSDD FFASCENLIN PADPIRKAGV
     FVETGAWYDG WETRRHNTAP CDWVIVKLGP SSGRVTGCEI DTTFFNGNHA PEVSVEAAFL
     PEGNPDAKTN WTPILPKLPC GPTQRHIYRF KEIPQQNFTH VRLCMYPDGG IARFRLYGNV
     VPVFPADLDA RLDLAHMYLG GLVVQCSDQH FGKKDNLLLP GRGVNMGDGW ETARSREKGH
     VDWVIVKLGA RGYIDDALID TNHFKGNYPK EVILEAIDSP DHIPGPDAQW VTILPARKLG
     PHMEHVFTNL QNNSTPMTHV RMIIIPDGGV KRLRIYGRRA AN