ID   ALLS_ECOK1              Reviewed;         308 AA.
AC   A1A8H0;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=HTH-type transcriptional activator AllS;
GN   Name=allS; OrderedLocusNames=Ecok1_04660; ORFNames=APECO1_1510;
OS   Escherichia coli O1:K1 / APEC.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=405955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17293413; DOI=10.1128/jb.01726-06;
RA   Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J.,
RA   Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.;
RT   "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7
RT   shares strong similarities with human extraintestinal pathogenic E. coli
RT   genomes.";
RL   J. Bacteriol. 189:3228-3236(2007).
CC   -!- FUNCTION: Positive regulator essential for the expression of allD
CC       operon. Binds to the allD promoter (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000468; ABI99959.1; -; Genomic_DNA.
DR   RefSeq; WP_000460112.1; NC_008563.1.
DR   AlphaFoldDB; A1A8H0; -.
DR   SMR; A1A8H0; -.
DR   EnsemblBacteria; ABI99959; ABI99959; APECO1_1510.
DR   KEGG; ecv:APECO1_1510; -.
DR   HOGENOM; CLU_039613_35_1_6; -.
DR   OMA; VYMGVWD; -.
DR   Proteomes; UP000008216; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..308
FT                   /note="HTH-type transcriptional activator AllS"
FT                   /id="PRO_0000312807"
FT   DOMAIN          2..59
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        19..38
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   308 AA;  34526 MW;  F1B525A0F63CBAEE CRC64;
     MFDPETLRTF IAVAETGSFS KAAERLCKTT ATISYRIKLL EENTGVALFF RTTRSVTLTA
     AGEHLLCQAR DWLGWLESMP SELQQVNDGV ERQVNIVINN LLYNPQAVAR LLAWLNERYP
     FTQFHISRQI YMGVWDSLLY EGFSLAIGVT GTEALANTFS LDPLGSVQWR FVMAADHPLA
     NVEEPLTEAQ LRRFPAVNIE DSARTLTKRV AWRLPGQKEI IVPDMETKIA AHLAGVGIGF
     LPKSLCQSML DNQQLVSRVI PTMRPPSPLS LAWRKFGSGK AVEDIVTLFT QRRPEISGFL
     EIFGNPRS