ALLS_ECOL5
ID ALLS_ECOL5 Reviewed; 308 AA.
AC Q0TKD7;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=HTH-type transcriptional activator AllS;
GN Name=allS; OrderedLocusNames=ECP_0565;
OS Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=362663;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=536 / UPEC;
RX PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT "Role of pathogenicity island-associated integrases in the genome
RT plasticity of uropathogenic Escherichia coli strain 536.";
RL Mol. Microbiol. 61:584-595(2006).
CC -!- FUNCTION: Positive regulator essential for the expression of allD
CC operon. Binds to the allD promoter (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000305}.
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DR EMBL; CP000247; ABG68594.1; -; Genomic_DNA.
DR RefSeq; WP_000460119.1; NC_008253.1.
DR AlphaFoldDB; Q0TKD7; -.
DR SMR; Q0TKD7; -.
DR STRING; 362663.ECP_0565; -.
DR EnsemblBacteria; ABG68594; ABG68594; ECP_0565.
DR KEGG; ecp:ECP_0565; -.
DR HOGENOM; CLU_039613_35_1_6; -.
DR OMA; VYMGVWD; -.
DR Proteomes; UP000009182; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Activator; DNA-binding; Transcription; Transcription regulation.
FT CHAIN 1..308
FT /note="HTH-type transcriptional activator AllS"
FT /id="PRO_0000312809"
FT DOMAIN 2..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT DNA_BIND 19..38
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ SEQUENCE 308 AA; 34556 MW; BC03FA8C44F79D70 CRC64;
MFDPETLRTF IAVAETGSFS KAAERLCKTT ATISYRIKLL EENTGVALFF RTTRSVTLTA
AGEHLLCQAR DWLSWLESMP SELQQVNDGV ERQVNIVINN LLYNPQAVAR LLAWLNERYP
FTQFHISRQI YMGVWDSLLY EGFSLAIGVT GTEALANTFS LDPLGSVQWR FVMAADHPLA
NVEEPLTEAQ LRRFPAVNIE DSARTLTKRV AWRLPGQKEI IVPDMETKIA AHLAGVGIGF
LPKSLCQSML DNQQLVSRVI PTMRPPSPLS LAWRKFGSGK AVEDIVTLFT QRRPEISGFL
EIFGNPRS