ALLS_ECOLI
ID ALLS_ECOLI Reviewed; 308 AA.
AC P0ACR0; P77702; Q2MBS4;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=HTH-type transcriptional activator AllS;
GN Name=allS; Synonyms=glxA1, ybbS; OrderedLocusNames=b0504, JW0492;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / ECL1;
RX PubMed=10601204; DOI=10.1128/jb.181.24.7479-7484.1999;
RA Cusa E., Obradors N., Baldoma L., Badia J., Aguilar J.;
RT "Genetic analysis of a chromosomal region containing genes required for
RT assimilation of allantoin nitrogen and linked glyoxylate metabolism in
RT Escherichia coli.";
RL J. Bacteriol. 181:7479-7484(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP FUNCTION, DNA-BINDING, AND INDUCTION.
RC STRAIN=K12;
RX PubMed=12460564; DOI=10.1016/s0022-2836(02)01134-8;
RA Rintoul M.R., Cusa E., Baldoma L., Badia J., Reitzer L., Aguilar J.;
RT "Regulation of the Escherichia coli allantoin regulon: coordinated function
RT of the repressor AllR and the activator AllS.";
RL J. Mol. Biol. 324:599-610(2002).
CC -!- FUNCTION: Positive regulator essential for the expression of allD
CC operon. Binds to the allD promoter. {ECO:0000269|PubMed:12460564}.
CC -!- INDUCTION: Induced anaerobically and by nitrogen limitation. Repressed
CC by AllR. {ECO:0000269|PubMed:12460564}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000305}.
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DR EMBL; U89024; AAB93845.1; -; Genomic_DNA.
DR EMBL; U82664; AAB40257.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73606.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76282.1; -; Genomic_DNA.
DR PIR; G64781; G64781.
DR RefSeq; NP_415037.1; NC_000913.3.
DR RefSeq; WP_000460145.1; NZ_STEB01000007.1.
DR AlphaFoldDB; P0ACR0; -.
DR SMR; P0ACR0; -.
DR BioGRID; 4259497; 7.
DR BioGRID; 849528; 1.
DR IntAct; P0ACR0; 4.
DR STRING; 511145.b0504; -.
DR PaxDb; P0ACR0; -.
DR PRIDE; P0ACR0; -.
DR DNASU; 945139; -.
DR EnsemblBacteria; AAC73606; AAC73606; b0504.
DR EnsemblBacteria; BAE76282; BAE76282; BAE76282.
DR GeneID; 66671200; -.
DR GeneID; 945139; -.
DR KEGG; ecj:JW0492; -.
DR KEGG; eco:b0504; -.
DR PATRIC; fig|1411691.4.peg.1773; -.
DR EchoBASE; EB3053; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_35_1_6; -.
DR InParanoid; P0ACR0; -.
DR OMA; VYMGVWD; -.
DR PhylomeDB; P0ACR0; -.
DR BioCyc; EcoCyc:G6274-MON; -.
DR PRO; PR:P0ACR0; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:EcoCyc.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:EcoCyc.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:EcoCyc.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..308
FT /note="HTH-type transcriptional activator AllS"
FT /id="PRO_0000105776"
FT DOMAIN 2..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT DNA_BIND 19..38
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ SEQUENCE 308 AA; 34512 MW; 42A4727F078CE0B6 CRC64;
MFDPETLRTF IAVAETGSFS KAAERLCKTT ATISYRIKLL EENTGVALFF RTTRSVTLTA
AGEHLLSQAR DWLSWLESMP SELQQVNDGV ERQVNIVINN LLYNPQAVAQ LLAWLNERYP
FTQFHISRQI YMGVWDSLLY EGFSLAIGVT GTEALANTFS LDPLGSVQWR FVMAADHPLA
NVEEPLTEAQ LRRFPAVNIE DSARTLTKRV AWRLPGQKEI IVPDMETKIA AHLAGVGIGF
LPKSLCQSMI DNQQLVSRVI PTMRPPSPLS LAWRKFGSGK AVEDIVTLFT QRRPEISGFL
EIFGNPRS
