ID   ALLS_SALTI              Reviewed;         308 AA.
AC   Q8Z8R3; Q7C8C7;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 129.
DE   RecName: Full=HTH-type transcriptional activator AllS;
GN   Name=allS; OrderedLocusNames=STY0562, t2346;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Positive regulator essential for the expression of allD
CC       operon. Binds to the allD promoter (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; AE014613; AAO69938.1; -; Genomic_DNA.
DR   EMBL; AL513382; CAD04999.1; -; Genomic_DNA.
DR   RefSeq; NP_455109.1; NC_003198.1.
DR   RefSeq; WP_000460171.1; NZ_WSUR01000008.1.
DR   AlphaFoldDB; Q8Z8R3; -.
DR   SMR; Q8Z8R3; -.
DR   STRING; 220341.16501784; -.
DR   EnsemblBacteria; AAO69938; AAO69938; t2346.
DR   KEGG; stt:t2346; -.
DR   KEGG; sty:STY0562; -.
DR   PATRIC; fig|220341.7.peg.563; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_35_1_6; -.
DR   OMA; VYMGVWD; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..308
FT                   /note="HTH-type transcriptional activator AllS"
FT                   /id="PRO_0000312813"
FT   DOMAIN          2..59
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        19..38
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   308 AA;  34259 MW;  DE9C5E77493E36A0 CRC64;
     MFDPETLRTF ISVAETGSFS KAAERLCKTT ATTSYRIKLL EENTGVGLFF RTTRSVSLTA
     AGSHLLSQAK DWLAWLDSMP DELRQVNDGV ERQVNIVVNN LLYSPQAVAS LLSWLNARYP
     FTQFHFSRQI YMGVWDSLLY EGFSLAIGVT GTEPLANTFM LDPLGSVQWR FVMSADHPLA
     HVSGPLTEAQ LRRFPAINIE DSARTLTKRV AWRLPGQKEI IVPDMETKIA AHLAGVGIGF
     VPQPLCQTLI DKNELVSCTI PTMRPPSPLS LAWHKFGGGK AVEDIVKLFT QRQPEIAGFL
     SIFNTVRC