GD1L1_MOUSE
ID GD1L1_MOUSE Reviewed; 370 AA.
AC Q8VE33; A2A5I0;
DT 07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Ganglioside-induced differentiation-associated protein 1-like 1;
DE Short=GDAP1-L1;
GN Name=Gdap1l1; Synonyms=Gdap1l;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SIMILARITY: Belongs to the GST superfamily. {ECO:0000305}.
CC -!- CAUTION: While belonging to the GST superfamily, it probably lacks
CC glutathione transferase activity. {ECO:0000305}.
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DR EMBL; AL591488; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC019941; AAH19941.1; -; mRNA.
DR AlphaFoldDB; Q8VE33; -.
DR SMR; Q8VE33; -.
DR STRING; 10090.ENSMUSP00000018087; -.
DR iPTMnet; Q8VE33; -.
DR PhosphoSitePlus; Q8VE33; -.
DR SwissPalm; Q8VE33; -.
DR MaxQB; Q8VE33; -.
DR PaxDb; Q8VE33; -.
DR PRIDE; Q8VE33; -.
DR ProteomicsDB; 265738; -.
DR Antibodypedia; 27351; 159 antibodies from 19 providers.
DR Ensembl; ENSMUST00000109421; ENSMUSP00000105048; ENSMUSG00000017943.
DR UCSC; uc012ciq.1; mouse.
DR MGI; MGI:2385163; Gdap1l1.
DR VEuPathDB; HostDB:ENSMUSG00000017943; -.
DR eggNOG; KOG4420; Eukaryota.
DR GeneTree; ENSGT00940000160178; -.
DR HOGENOM; CLU_049129_1_0_1; -.
DR InParanoid; Q8VE33; -.
DR PhylomeDB; Q8VE33; -.
DR PRO; PR:Q8VE33; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q8VE33; protein.
DR Bgee; ENSMUSG00000017943; Expressed in embryonic brain and 123 other tissues.
DR ExpressionAtlas; Q8VE33; baseline and differential.
DR Genevisible; Q8VE33; MM.
DR GO; GO:0006749; P:glutathione metabolic process; IEA:InterPro.
DR InterPro; IPR034336; GDAP1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR004045; Glutathione_S-Trfase_N.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR44188:SF2; PTHR44188:SF2; 1.
DR Pfam; PF13417; GST_N_3; 1.
DR SUPFAM; SSF47616; SSF47616; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
DR PROSITE; PS50405; GST_CTER; 1.
DR PROSITE; PS50404; GST_NTER; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..370
FT /note="Ganglioside-induced differentiation-associated
FT protein 1-like 1"
FT /id="PRO_0000186041"
FT DOMAIN 45..129
FT /note="GST N-terminal"
FT DOMAIN 177..344
FT /note="GST C-terminal"
SQ SEQUENCE 370 AA; 42318 MW; 7ACDD616D8A9D399 CRC64;
MATPNNLTPT NCSWWPISAL ESDAAKPVET PDAPEASSPA HWPKESLVLY HWTQSFSSQK
RLQVRLVIAE KGLACEERDV SLPQSEHKEP WFMRLNLGEE VPVIIHRDNI ISDYDQIIDY
VERTFTGEHV VALMPEAGSP QHARVLQYRE LLDALPMDAY THGCILHPEL TTDSMIPKYA
TAEIRRHLAN ATTDLMKLDH EEEPQLSEPY LSKQKKLMAK ILEHDDVSYL KKILGELAMV
LDQIEAELEK RKLENEGQTC ELWLCGCAFT LADVLLGATL HRLKFLGLSK KYWEDGSRPN
LQSFFERVQR RFAFRKVLGD IHTTLLSAVI PNAFRLVKRK PPSFFGASFL MGSLGGMGYF
AYWYLKKKYI