ID   GDAP2_DANRE             Reviewed;         504 AA.
AC   Q66HX8;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Ganglioside-induced differentiation-associated protein 2;
GN   Name=gdap2;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GDAP2 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC081629; AAH81629.1; -; mRNA.
DR   RefSeq; NP_001004563.1; NM_001004563.1.
DR   AlphaFoldDB; Q66HX8; -.
DR   SMR; Q66HX8; -.
DR   STRING; 7955.ENSDARP00000030237; -.
DR   PaxDb; Q66HX8; -.
DR   GeneID; 447824; -.
DR   KEGG; dre:447824; -.
DR   CTD; 54834; -.
DR   ZFIN; ZDB-GENE-040912-31; gdap2.
DR   eggNOG; KOG2633; Eukaryota.
DR   InParanoid; Q66HX8; -.
DR   OrthoDB; 937161at2759; -.
DR   PhylomeDB; Q66HX8; -.
DR   PRO; PR:Q66HX8; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   CDD; cd02905; Macro_GDAP2-like; 1.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.220.10; -; 1.
DR   Gene3D; 3.40.525.10; -; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   InterPro; IPR035793; Macro_GDAP2.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF01661; Macro; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF52087; SSF52087; 1.
DR   SUPFAM; SSF52949; SSF52949; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..504
FT                   /note="Ganglioside-induced differentiation-associated
FT                   protein 2"
FT                   /id="PRO_0000331398"
FT   DOMAIN          54..234
FT                   /note="Macro"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00490"
FT   DOMAIN          342..490
FT                   /note="CRAL-TRIO"
FT   REGION          20..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..46
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   504 AA;  57515 MW;  764B62FBD3B9C3E4 CRC64;
     MDPLGARSQF VEVLNLPTWD QPQGVQDELD GENHYEEEEE EEEDNLTNQL NSVNSPFTFR
     QDINNKIVLF NGDVALLNCT AIVNTSNETL TDKNPISDSI HRHAGPELRD ELLKLKGCRT
     GEAKMTEGFD LAARFIIHTV GPKYKAKYRT AAESSLYSCY RNVLQLAKEH AMVSVGFCVI
     STVKRAYPVE DATHIALRTV RRFLENHGEN IETLVFAVSD VEEPVYRKLL PLYYPRSKQE
     ERISLPLLPA DIGNSEGEPV VPERQIRIAE KPVNLEDDPE DDSLDSDLGL VGSHAFARME
     GDVDKQRKLI LQGQMSEVAQ QKQHQRNYNR WLCKARAEDL SDIAALKALY QTGVDLCGRT
     VMVVVGRNIP VMLIDMEKAL LYFIHVMDHI TVKEYVMVYF HTLTGEHNHL DTDFLKKLYD
     IVDAKFKKNL RAFYFVHPTF RSKVSTWFFT TFSVSGLKDK VHHIENLQQL FTCVLPEQID
     IPPFVLEYDS RVNSPYYSAQ SAGL