ID   GDAP2_DROPS             Reviewed;         542 AA.
AC   Q292F9;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Protein GDAP2 homolog;
GN   ORFNames=GA15091;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- SIMILARITY: Belongs to the GDAP2 family. {ECO:0000305}.
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DR   EMBL; CM000071; EAL24903.1; -; Genomic_DNA.
DR   RefSeq; XP_001360328.1; XM_001360291.3.
DR   AlphaFoldDB; Q292F9; -.
DR   SMR; Q292F9; -.
DR   STRING; 7237.FBpp0277428; -.
DR   EnsemblMetazoa; FBtr0278990; FBpp0277428; FBgn0075116.
DR   GeneID; 4803643; -.
DR   KEGG; dpo:Dpse_GA15091; -.
DR   eggNOG; KOG2633; Eukaryota.
DR   HOGENOM; CLU_026877_0_0_1; -.
DR   InParanoid; Q292F9; -.
DR   OMA; LYFPRDR; -.
DR   PhylomeDB; Q292F9; -.
DR   Proteomes; UP000001819; Chromosome 3.
DR   Bgee; FBgn0075116; Expressed in insect adult head and 2 other tissues.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:EnsemblMetazoa.
DR   GO; GO:0042594; P:response to starvation; IEA:EnsemblMetazoa.
DR   CDD; cd02905; Macro_GDAP2-like; 1.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.220.10; -; 1.
DR   Gene3D; 3.40.525.10; -; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   InterPro; IPR035793; Macro_GDAP2.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF01661; Macro; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF52087; SSF52087; 1.
DR   SUPFAM; SSF52949; SSF52949; 1.
DR   PROSITE; PS50191; CRAL_TRIO; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..542
FT                   /note="Protein GDAP2 homolog"
FT                   /id="PRO_0000331402"
FT   DOMAIN          58..237
FT                   /note="Macro"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00490"
FT   DOMAIN          373..530
FT                   /note="CRAL-TRIO"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00056"
FT   REGION          277..304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        282..300
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   542 AA;  61631 MW;  5F5B6966BEACB7E7 CRC64;
     MRLDTNSNVD FKAFESSSSS SSCLVKLDNL ATWGGSQKTD TRLPITDYST LGGPRHNRSP
     FPLSKDVNNR LVIWDGDMTT LDVDAITNTS DETLTESNII SERILAVAGN QLREELSTNV
     KECRTGDVRI TRGYNLPAKY VLHTVAPTYR EKFKTAAENT LHCCYRNVLC KAKELNLHTI
     ALCNISVHQK SFPADVAAHI ALRTIRRYLD KCTLQVVILC VNSNERGTYE VLAPLYFPRD
     QLEERSALWQ LPKDIGGEFG EPQHPDPDRQ IRIIRNPQHS VHMRHGHTDD DSDVSPHDME
     GNSSDLEYGA KDMNGLSPNS YSSGLQTQLQ RDLDRQHLLS DRPRAGVYEN VISEGVEGIE
     HQERYERLLR RAQVEDLTEV SGIGCLYQSG VDRLGRPVIV FCGKWFPAQN IDLEKALLYL
     IKLLDPIVKG DYVISYFHTL TSTNNYPSLH WLREVYSVLP YKYKKNLKAF YIVHPTFWTK
     MMTWWFTTFM APAIKAKVHS LPGVEHLYSA ITKDQLEIPA YITEYDMATN GLHYFNPVPT
     AS