ID   GDAP2_RAT               Reviewed;         497 AA.
AC   Q66H63;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Ganglioside-induced differentiation-associated-protein 2;
GN   Name=Gdap2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the GDAP2 family. {ECO:0000305}.
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DR   EMBL; BC082000; AAH82000.1; -; mRNA.
DR   RefSeq; NP_001013219.1; NM_001013201.1.
DR   RefSeq; XP_006233094.1; XM_006233032.3.
DR   AlphaFoldDB; Q66H63; -.
DR   SMR; Q66H63; -.
DR   STRING; 10116.ENSRNOP00000026953; -.
DR   PaxDb; Q66H63; -.
DR   PeptideAtlas; Q66H63; -.
DR   GeneID; 362004; -.
DR   KEGG; rno:362004; -.
DR   UCSC; RGD:1306050; rat.
DR   CTD; 54834; -.
DR   RGD; 1306050; Gdap2.
DR   VEuPathDB; HostDB:ENSRNOG00000019754; -.
DR   eggNOG; KOG2633; Eukaryota.
DR   HOGENOM; CLU_026877_0_0_1; -.
DR   InParanoid; Q66H63; -.
DR   OMA; LYFPRDR; -.
DR   OrthoDB; 937161at2759; -.
DR   PRO; PR:Q66H63; -.
DR   Proteomes; UP000002494; Chromosome 2.
DR   Bgee; ENSRNOG00000019754; Expressed in brain and 20 other tissues.
DR   Genevisible; Q66H63; RN.
DR   GO; GO:0032526; P:response to retinoic acid; ISO:RGD.
DR   CDD; cd02905; Macro_GDAP2-like; 1.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.220.10; -; 1.
DR   Gene3D; 3.40.525.10; -; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   InterPro; IPR035793; Macro_GDAP2.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF01661; Macro; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF52087; SSF52087; 1.
DR   SUPFAM; SSF52949; SSF52949; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..497
FT                   /note="Ganglioside-induced differentiation-associated-
FT                   protein 2"
FT                   /id="PRO_0000331397"
FT   DOMAIN          43..223
FT                   /note="Macro"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00490"
FT   DOMAIN          333..481
FT                   /note="CRAL-TRIO"
FT   MOD_RES         280
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NXN4"
SQ   SEQUENCE   497 AA;  56130 MW;  3F267B9C833E2AA9 CRC64;
     MDPLGAPSQF VDVDTLVSWG DSYEDEVNSS DSTAEAFQED SNRSPFLYNR DINGKVVLWK
     GDVALLNCTA IVNTSNESLT DKNPVSESIF MLAGPDLKED LQKLKGCRTG EAKLTKGFNL
     AARFIIHTVG PKYKSRYRTA AESSLYSCYR NVLQLAKEQS MSSVGFCVIN SAKRGYPLED
     ATHIALRTVR RFLEIHGETI EKVVFAISEL EEATYQKLLP LYFPRSLKEE SQSLPSLPAD
     IGNAEGEPVV PERQIRISEK PGASEDHEED EDEGLGVDLS FIGSHAFARM EGDIDKQRKL
     ILQGQLSEAA LQKQHQRNYN RWLCQARSED LSDIASLKAL YQTGVDNCGR TVMVVVGRNI
     PVTLIDMDKA LLYFIHVMDH IAVKEYVLVY FHTLTSEYNH LDSDFLKKLY DVVDIKYKRN
     LKAVYFVHPT FRSKVSTWFF TTFSVSGLKD KIHHVDSLQQ LFSAISPEQI DFPPFVLEYD
     ARENGPYFAS YPPSPDL