ID   GDAP2_XENTR             Reviewed;         496 AA.
AC   Q5CZL1;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Ganglioside-induced differentiation-associated protein 2;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GDAP2 family. {ECO:0000305}.
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DR   EMBL; BC090810; AAH90810.1; -; mRNA.
DR   RefSeq; NP_001015874.1; NM_001015874.1.
DR   AlphaFoldDB; Q5CZL1; -.
DR   SMR; Q5CZL1; -.
DR   DNASU; 548591; -.
DR   GeneID; 548591; -.
DR   KEGG; xtr:548591; -.
DR   CTD; 54834; -.
DR   Xenbase; XB-GENE-996028; gdap2.
DR   eggNOG; KOG2633; Eukaryota.
DR   InParanoid; Q5CZL1; -.
DR   OrthoDB; 937161at2759; -.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000009921; Expressed in skeletal muscle tissue and 13 other tissues.
DR   CDD; cd02905; Macro_GDAP2-like; 1.
DR   CDD; cd00170; SEC14; 1.
DR   Gene3D; 3.40.220.10; -; 1.
DR   Gene3D; 3.40.525.10; -; 1.
DR   InterPro; IPR001251; CRAL-TRIO_dom.
DR   InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR   InterPro; IPR002589; Macro_dom.
DR   InterPro; IPR043472; Macro_dom-like.
DR   InterPro; IPR035793; Macro_GDAP2.
DR   Pfam; PF13716; CRAL_TRIO_2; 1.
DR   Pfam; PF01661; Macro; 1.
DR   SMART; SM00506; A1pp; 1.
DR   SMART; SM00516; SEC14; 1.
DR   SUPFAM; SSF52087; SSF52087; 1.
DR   SUPFAM; SSF52949; SSF52949; 1.
DR   PROSITE; PS51154; MACRO; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..496
FT                   /note="Ganglioside-induced differentiation-associated
FT                   protein 2"
FT                   /id="PRO_0000331400"
FT   DOMAIN          44..224
FT                   /note="Macro"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00490"
FT   DOMAIN          329..483
FT                   /note="CRAL-TRIO"
FT   REGION          22..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          252..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..39
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   496 AA;  55890 MW;  EB2DB038CFE6009D CRC64;
     MDPLGARSCF VDADALPCWA DVRDGEGEDV PDGGRKDAPH GGLHSPFPYR NDINKKVILW
     RGDVALLSCT ALVNTSNETL TDKNPVSDSI FRYSGPELSE EMQKLKGCRT GEAKLTKGFN
     LAARYIIHTV GPKYKTKYRT AAESSLYSCY RNVLQLAKEQ GMASVGFCVI ATQKRCYPPE
     DSTHIALRTV RRFLEAHGAA LEKVVFAVTE QEEGTYRRLL PLYFPRSLEE EQRSIPFLPQ
     DIGNAEGEPV VPERQIRISE KPGGQDDDSE EEGLVKDLSV IGSHAFARME GDVDKQRRLA
     LQGQLSGAAM QKQHQRNYNR WLSRARTEDL SDIAALKALY QSGVDNCGRT VMVVVGRNIP
     VLLIDMEKAL LYFIHMMDHV AAKEYVLVYF HTLTGEHNHP DSDFLKNMYD IVDVKYKKNL
     KALYFVHPTF RSKVSSWFFT TFTVSGLKDK VHQVESLHQL FSAVPPEQIE IPPFVLDYDA
     RENGPFFPSQ SSFLSL