ID   GDI1_MAGO7              Reviewed;         464 AA.
AC   G4MT60;
DT   07-OCT-2020, integrated into UniProtKB/Swiss-Prot.
DT   14-DEC-2011, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Rab GDP-dissociation inhibitor;
DE            Short=Rab GDI;
GN   Name=GDI1; ORFNames=MGG_07137;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
RN   [2]
RP   INTERACTION WITH YPT7, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=29308611; DOI=10.1631/jzus.b1700336;
RA   Huang L.Y., Wu M., Yu X.Y., Li L., Lin F.C., Liu X.H.;
RT   "Physical interactions and mutational analysis of MoYpt7 in Magnaporthe
RT   oryzae.";
RL   J. Zhejiang Univ. Sci. B 19:79-84(2018).
CC   -!- FUNCTION: Regulates the GDP/GTP exchange reaction of YPT7 by inhibiting
CC       the dissociation of GDP from it, and the subsequent binding of GTP to
CC       YTP7. {ECO:0000269|PubMed:29308611}.
CC   -!- SUBUNIT: Interacts with the GDP-bound form of Rab GTPase YPT7.
CC       {ECO:0000269|PubMed:29308611}.
CC   -!- SIMILARITY: Belongs to the Rab GDI family. {ECO:0000305}.
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DR   EMBL; CM001232; EHA55525.1; -; Genomic_DNA.
DR   RefSeq; XP_003715332.1; XM_003715284.1.
DR   AlphaFoldDB; G4MT60; -.
DR   SMR; G4MT60; -.
DR   STRING; 318829.MGG_07137T0; -.
DR   EnsemblFungi; MGG_07137T0; MGG_07137T0; MGG_07137.
DR   GeneID; 2683259; -.
DR   KEGG; mgr:MGG_07137; -.
DR   VEuPathDB; FungiDB:MGG_07137; -.
DR   eggNOG; KOG1439; Eukaryota.
DR   HOGENOM; CLU_021695_0_1_1; -.
DR   InParanoid; G4MT60; -.
DR   OMA; DHYGGES; -.
DR   OrthoDB; 763627at2759; -.
DR   Proteomes; UP000009058; Chromosome 2.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005093; F:Rab GDP-dissociation inhibitor activity; IEA:EnsemblFungi.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:EnsemblFungi.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR018203; GDP_dissociation_inhibitor.
DR   InterPro; IPR000806; RabGDI.
DR   PANTHER; PTHR11787; PTHR11787; 1.
DR   Pfam; PF00996; GDI; 1.
DR   PRINTS; PR00892; RABGDI.
DR   PRINTS; PR00891; RABGDIREP.
DR   SUPFAM; SSF51905; SSF51905; 2.
PE   1: Evidence at protein level;
KW   GTPase activation; Reference proteome.
FT   CHAIN           1..464
FT                   /note="Rab GDP-dissociation inhibitor"
FT                   /id="PRO_0000451054"
SQ   SEQUENCE   464 AA;  50928 MW;  A85CF1DADBE0EFBB CRC64;
     MEEIAKEYDV IVLGTGLTEC ILSGVLSVKG KKVLHIDRND HYGGEAASLN LQALFKKYGN
     YNSGEEPWAK YGRNTDWNID LVPKFLMSSG ELTNILVSTD VTRYLEFKQV AGSFVQQGSG
     PKATVAKVPS DAAEALRSPL MGIFEKRRMK SFIEWVGTFD LKDPATHKGL DLSSCTMKDV
     YDKFGLETGT KDFIGHAMAL YLSDDYISKP GGAPEAIDRI RLYGNSVARY GKSPYIYPLF
     GLGDLPQGFA RLSAIYGGTY MLNTNIDELL YEDGKAVGIK ATMTGIEPEM KFETRAKMIL
     GDPSYFSDKV KVVGHVLRAI CVLKHPLAGT SDADSCQLII PQSQVGRKND IYIACVSSAH
     SVCPKGYYIA IVSTIAETSA NHHLELQPGL ERLGKIEEQF MGPPIPLYAP IEDGTSSGIF
     ISKSYDATSH FETTTDDVKD IYRRATGEEL KVEGLRDLQV AGDE