ID   GDI1_SCHPO              Reviewed;         440 AA.
AC   Q10305;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 131.
DE   RecName: Full=Probable secretory pathway GDP dissociation inhibitor 1;
GN   Name=gdi1; Synonyms=sec19; ORFNames=SPAC22H10.12c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SIMILARITY: Belongs to the Rab GDI family. {ECO:0000305}.
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DR   EMBL; CU329670; CAA93612.1; -; Genomic_DNA.
DR   PIR; T38215; T38215.
DR   RefSeq; NP_593749.1; NM_001019180.2.
DR   AlphaFoldDB; Q10305; -.
DR   SMR; Q10305; -.
DR   BioGRID; 278221; 9.
DR   STRING; 4896.SPAC22H10.12c.1; -.
DR   MaxQB; Q10305; -.
DR   PaxDb; Q10305; -.
DR   PRIDE; Q10305; -.
DR   EnsemblFungi; SPAC22H10.12c.1; SPAC22H10.12c.1:pep; SPAC22H10.12c.
DR   GeneID; 2541727; -.
DR   KEGG; spo:SPAC22H10.12c; -.
DR   PomBase; SPAC22H10.12c; gdi1.
DR   VEuPathDB; FungiDB:SPAC22H10.12c; -.
DR   eggNOG; KOG1439; Eukaryota.
DR   HOGENOM; CLU_021695_0_0_1; -.
DR   InParanoid; Q10305; -.
DR   OMA; DHYGGES; -.
DR   PhylomeDB; Q10305; -.
DR   Reactome; R-SPO-6798695; Neutrophil degranulation.
DR   Reactome; R-SPO-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR   PRO; PR:Q10305; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0032153; C:cell division site; HDA:PomBase.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005093; F:Rab GDP-dissociation inhibitor activity; ISO:PomBase.
DR   GO; GO:0006886; P:intracellular protein transport; IC:PomBase.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; ISO:PomBase.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR018203; GDP_dissociation_inhibitor.
DR   InterPro; IPR000806; RabGDI.
DR   PANTHER; PTHR11787; PTHR11787; 1.
DR   Pfam; PF00996; GDI; 1.
DR   PRINTS; PR00892; RABGDI.
DR   PRINTS; PR00891; RABGDIREP.
DR   SUPFAM; SSF51905; SSF51905; 2.
PE   3: Inferred from homology;
KW   Protein transport; Reference proteome; Transport.
FT   CHAIN           1..440
FT                   /note="Probable secretory pathway GDP dissociation
FT                   inhibitor 1"
FT                   /id="PRO_0000056685"
SQ   SEQUENCE   440 AA;  49556 MW;  31182533301A53A6 CRC64;
     MDEEYDVIVL GTGLTECVLS GLLSVDGKKV LHIDRNDYYG ADSASLNLTQ LYALFRPGEQ
     RPESLGRDRD WCVDLVPKFL MANGDLTNIL IYTDVTRYIE FKQIAGSYVY RDGRIAKVPG
     NEMEALKSPL MSLFEKRRAK KFLEWVNNYR EDDPSTYKDI NIDRDSMESV FKKFGLQSGT
     QDFIGHAMAL YLDDAYLKKP ARETRERILL YASSIAKFGK SPYIYPLYGL GELPQGFARL
     SAIYGGTYML NQPVDEIVYG DDGVAIGVRS GDQVAKAKQI IGDPSYFREK VRSVGRLVRA
     ICILNHPIPN TDNLDSVQII IPQNQVKRKH DIYIAGISSV HNVCPKGYYL AIISTIVETA
     NPLSEIAPGL KLLGPVVESF SRVQEIYEPV TDGTKDQCYI SKSVDATSHF ETLTCDVRDI
     YKRMTGTDLV LKQRPKMEDQ