ID   GDI_ARATH               Reviewed;         445 AA.
AC   Q9LXC0;
DT   19-MAR-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 107.
DE   RecName: Full=Guanosine nucleotide diphosphate dissociation inhibitor At5g09550;
DE            Short=AtGDI;
GN   OrderedLocusNames=At5g09550; ORFNames=F17I14.260;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- FUNCTION: Regulates the GDP/GTP exchange reaction of most RAB proteins
CC       by inhibiting the dissociation of GDP from them, and the subsequent
CC       binding of GTP. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Rab GDI family. {ECO:0000305}.
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DR   EMBL; AL353994; CAB89375.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED91409.1; -; Genomic_DNA.
DR   PIR; T49943; T49943.
DR   RefSeq; NP_196517.3; NM_120992.5.
DR   AlphaFoldDB; Q9LXC0; -.
DR   SMR; Q9LXC0; -.
DR   STRING; 3702.AT5G09550.1; -.
DR   iPTMnet; Q9LXC0; -.
DR   PaxDb; Q9LXC0; -.
DR   PRIDE; Q9LXC0; -.
DR   ProteomicsDB; 221964; -.
DR   EnsemblPlants; AT5G09550.1; AT5G09550.1; AT5G09550.
DR   GeneID; 830814; -.
DR   Gramene; AT5G09550.1; AT5G09550.1; AT5G09550.
DR   KEGG; ath:AT5G09550; -.
DR   Araport; AT5G09550; -.
DR   TAIR; locus:2144741; AT5G09550.
DR   eggNOG; KOG1439; Eukaryota.
DR   HOGENOM; CLU_021695_0_0_1; -.
DR   InParanoid; Q9LXC0; -.
DR   OMA; YIPTDLG; -.
DR   OrthoDB; 763627at2759; -.
DR   PhylomeDB; Q9LXC0; -.
DR   PRO; PR:Q9LXC0; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LXC0; baseline and differential.
DR   Genevisible; Q9LXC0; AT.
DR   GO; GO:0048046; C:apoplast; IDA:TAIR.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0005093; F:Rab GDP-dissociation inhibitor activity; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IBA:GO_Central.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR018203; GDP_dissociation_inhibitor.
DR   InterPro; IPR000806; RabGDI.
DR   PANTHER; PTHR11787; PTHR11787; 1.
DR   Pfam; PF00996; GDI; 1.
DR   PRINTS; PR00892; RABGDI.
DR   PRINTS; PR00891; RABGDIREP.
DR   SUPFAM; SSF51905; SSF51905; 2.
PE   3: Inferred from homology;
KW   GTPase activation; Reference proteome.
FT   CHAIN           1..445
FT                   /note="Guanosine nucleotide diphosphate dissociation
FT                   inhibitor At5g09550"
FT                   /id="PRO_0000425809"
SQ   SEQUENCE   445 AA;  49549 MW;  D68E81E4417FE8C2 CRC64;
     MDEEYDVIVL GTGLKECILS GLLSVDGLKV LHMDRNDYYG GESSSLNLTQ LWKRFRGSDT
     PEENLGASRE YNVDMIPKFI MANGLLVQTL IHTDVTKYLN FKAVDGSFVY KKGKIYKVPA
     TDVEALKSPL MGLFEKRRAR KFFIYVQDYD EKDPKSHEGL DLSKVTAREI ISKYGLEDDT
     IDFIGHALAL HNDDDYLDQP AIDFVKRIKL YAESLARFQG GSPYIYPLYG LGELPQAFAR
     LSAVYGGTYM LNKPECKVEF DGSGKAIGVT SAGETAKCKK VVCDPSYLSE KVKKVGKVTR
     AVCIMSHPIP DTNDAHSVQI ILPQKQLGRK SDMYLFCCSY AHNVAPKGKY IAFVSAEAET
     DNPEEELKPG IELLGPTDEI FYHSYDTYVP TNIQEEDNCF ISATYDATTH FESTVVDVLD
     MYTKITGKTL DLSVDLSAAS AAAEN