GDL13_ARATH
ID GDL13_ARATH Reviewed; 384 AA.
AC Q38894; Q9SHP9; Q9SHQ1;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=GDSL esterase/lipase At1g28670;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g28670;
DE Flags: Precursor;
GN OrderedLocusNames=At1g28670; ORFNames=F1K23.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=8549779; DOI=10.1016/0014-5793(95)01405-5;
RA Brick D.J., Brumlik M.J., Buckley J.T., Cao J.X., Davies P.C., Misra S.,
RA Tranbarger T.J., Upton C.;
RT "A new family of lipolytic plant enzymes with members in rice, arabidopsis
RT and maize.";
RL FEBS Lett. 377:475-480(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [6]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF24544.2; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 4 genes: At1g28640, At1g28650, At1g28660 and At1g28670.; Evidence={ECO:0000305};
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DR EMBL; U38916; AAA93262.1; -; mRNA.
DR EMBL; AC007508; AAF24544.2; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31012.1; -; Genomic_DNA.
DR EMBL; AK118766; BAC43359.1; -; mRNA.
DR PIR; S68410; S68410.
DR RefSeq; NP_174188.1; NM_102634.3.
DR AlphaFoldDB; Q38894; -.
DR SMR; Q38894; -.
DR IntAct; Q38894; 1.
DR STRING; 3702.AT1G28670.1; -.
DR PaxDb; Q38894; -.
DR PRIDE; Q38894; -.
DR ProteomicsDB; 224749; -.
DR EnsemblPlants; AT1G28670.1; AT1G28670.1; AT1G28670.
DR GeneID; 839767; -.
DR Gramene; AT1G28670.1; AT1G28670.1; AT1G28670.
DR KEGG; ath:AT1G28670; -.
DR Araport; AT1G28670; -.
DR TAIR; locus:2018693; AT1G28670.
DR eggNOG; ENOG502QSMM; Eukaryota.
DR HOGENOM; CLU_015101_2_1_1; -.
DR OMA; PSILCGH; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q38894; -.
DR BioCyc; ARA:AT1G28670-MON; -.
DR BRENDA; 3.1.1.49; 399.
DR PRO; PR:Q38894; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q38894; baseline and differential.
DR Genevisible; Q38894; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..384
FT /note="GDSL esterase/lipase At1g28670"
FT /id="PRO_0000367355"
FT ACT_SITE 42
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 346
FT /evidence="ECO:0000250"
FT ACT_SITE 349
FT /evidence="ECO:0000250"
FT CARBOHYD 105
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 138
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 321
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 384 AA; 42427 MW; 9C68ECFD7249628D CRC64;
MASSLKKLIS SFLLVLYSTT IIVASSESRC RRFKSIISFG DSIADTGNYL HLSDVNHLPQ
SAFLPYGESF FHPPSGRASN GRLIIDFIAE FLGLPYVPPY FGSQNVSFEQ GINFAVYGAT
ALDRAFLLGK GIESDFTNVS LSVQLDTFKQ ILPNLCASST RDCKEMLGDS LILMGEIGGN
DYNYPFFEGK SINEIKELVP LIVKAISSAI VDLIDLGGKT FLVPGGFPTG CSAAYLTLFQ
TVAEKDQDPL TGCYPLLNEF GEHHNEQLKT ELKRLQKFYP HVNIIYADYH NSLYRFYQEP
AKYGFKNKPL AACCGVGGKY NFTIGKECGY EGVNYCQNPS EYVNWDGYHL TEAAYQKMTE
GILNGPYATP AFDWSCLGSG TVDT
