GDL15_ARATH
ID GDL15_ARATH Reviewed; 363 AA.
AC Q9C7N4; Q8LD01;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=GDSL esterase/lipase At1g29670;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g29670;
DE Flags: Precursor;
GN OrderedLocusNames=At1g29670; ORFNames=F15D2.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [6]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC068667; AAG51758.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31116.1; -; Genomic_DNA.
DR EMBL; AY065046; AAL57681.1; -; mRNA.
DR EMBL; AY086296; AAM64368.1; -; mRNA.
DR PIR; A86420; A86420.
DR RefSeq; NP_174260.1; NM_102707.5.
DR AlphaFoldDB; Q9C7N4; -.
DR SMR; Q9C7N4; -.
DR BioGRID; 25079; 3.
DR STRING; 3702.AT1G29670.1; -.
DR iPTMnet; Q9C7N4; -.
DR PaxDb; Q9C7N4; -.
DR PRIDE; Q9C7N4; -.
DR ProteomicsDB; 221965; -.
DR EnsemblPlants; AT1G29670.1; AT1G29670.1; AT1G29670.
DR GeneID; 839844; -.
DR Gramene; AT1G29670.1; AT1G29670.1; AT1G29670.
DR KEGG; ath:AT1G29670; -.
DR Araport; AT1G29670; -.
DR TAIR; locus:2013663; AT1G29670.
DR eggNOG; KOG0017; Eukaryota.
DR HOGENOM; CLU_015101_0_0_1; -.
DR InParanoid; Q9C7N4; -.
DR OMA; FAQQVPC; -.
DR PhylomeDB; Q9C7N4; -.
DR PRO; PR:Q9C7N4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C7N4; baseline and differential.
DR Genevisible; Q9C7N4; AT.
DR GO; GO:0048046; C:apoplast; HDA:TAIR.
DR GO; GO:0009534; C:chloroplast thylakoid; HDA:TAIR.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Hydrolase; Lipid degradation; Lipid metabolism; Reference proteome;
KW Secreted; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..363
FT /note="GDSL esterase/lipase At1g29670"
FT /id="PRO_0000367357"
FT ACT_SITE 39
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 327
FT /evidence="ECO:0000250"
FT ACT_SITE 330
FT /evidence="ECO:0000250"
FT CONFLICT 222
FT /note="A -> S (in Ref. 4; AAM64368)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 363 AA; 39872 MW; 0B733E210DD1B073 CRC64;
MESYLTKWCV VLVLLCFGFS VVKAQAQAQV PCFFVFGDSL VDNGNNNGLI SIARSNYFPY
GIDFGGPTGR FSNGKTTVDV IAELLGFNGY IPAYNTVSGR QILSGVNYAS AAAGIREETG
RQLGQRISFS GQVRNYQTTV SQVVQLLGDE TRAADYLKRC IYSVGLGSND YLNNYFMPTF
YSSSRQFTPE QYANDLISRY STQLNALYNY GARKFALSGI GAVGCSPNAL AGSPDGRTCV
DRINSANQIF NNKLRSLVDQ LNNNHPDAKF IYINAYGIFQ DMITNPARFG FRVTNAGCCG
IGRNAGQITC LPGQRPCRDR NAYVFWDAFH PTEAANVIIA RRSYNAQSAS DAYPMDISRL
AQL
