GDL17_ARATH
ID GDL17_ARATH Reviewed; 370 AA.
AC Q8L5Z1; Q9LQ33;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=GDSL esterase/lipase At1g33811;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g33811;
DE Flags: Precursor;
GN OrderedLocusNames=At1g33811; ORFNames=F14M2.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF97292.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC010164; AAF97292.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31628.1; -; Genomic_DNA.
DR EMBL; AY099832; AAM20683.1; -; mRNA.
DR EMBL; BT000322; AAN15641.1; -; mRNA.
DR PIR; F86461; F86461.
DR RefSeq; NP_564430.1; NM_103101.4.
DR AlphaFoldDB; Q8L5Z1; -.
DR SMR; Q8L5Z1; -.
DR STRING; 3702.AT1G33811.1; -.
DR PaxDb; Q8L5Z1; -.
DR PRIDE; Q8L5Z1; -.
DR ProteomicsDB; 221967; -.
DR EnsemblPlants; AT1G33811.1; AT1G33811.1; AT1G33811.
DR GeneID; 840274; -.
DR Gramene; AT1G33811.1; AT1G33811.1; AT1G33811.
DR KEGG; ath:AT1G33811; -.
DR Araport; AT1G33811; -.
DR TAIR; locus:505006166; AT1G33811.
DR eggNOG; ENOG502QQAP; Eukaryota.
DR HOGENOM; CLU_015101_0_0_1; -.
DR InParanoid; Q8L5Z1; -.
DR OMA; QPCEDRS; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q8L5Z1; -.
DR BioCyc; ARA:AT1G33811-MON; -.
DR PRO; PR:Q8L5Z1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8L5Z1; baseline and differential.
DR Genevisible; Q8L5Z1; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..370
FT /note="GDSL esterase/lipase At1g33811"
FT /id="PRO_0000367359"
FT ACT_SITE 41
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 336
FT /evidence="ECO:0000250"
FT ACT_SITE 339
FT /evidence="ECO:0000250"
FT CARBOHYD 203
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 241
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 242
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 370 AA; 41697 MW; B64EE26465B9BA92 CRC64;
MGILRFVLLI SLNLVLFGFK TTVSQPQQQA QVPCLFIFGD SLVDNGNNNR LLSLARANYR
PYGIDFPQGT TGRFTNGRTY VDALAQILGF RNYIPPYSRI RGQAILRGAN FASGAAGIRD
ETGDNLGAHT SMNQQVELYT TAVQQMLRYF RGDTNELQRY LSRCIFYSGM GSNDYLNNYF
MPDFYSTSTN YNDKTFAESL IKNYTQQLTR LYQFGARKVI VTGVGQIGCI PYQLARYNNR
NNSTGRCNEK INNAIVVFNT QVKKLVDRLN KGQLKGAKFV YLDSYKSTYD LAVNGAAYGF
EVVDKGCCGV GRNNGQITCL PLQTPCPDRT KYLFWDAFHP TETANILLAK SNFYSRAYTY
PINIQELANL
