GDL1_ARATH
ID GDL1_ARATH Reviewed; 360 AA.
AC Q9LMJ3; Q8LDE0;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 2.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=GDSL esterase/lipase At1g06990;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g06990;
DE Flags: Precursor;
GN OrderedLocusNames=At1g06990; ORFNames=F10K1.29;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF82220.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=AAM63265.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AC067971; AAF82220.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE28063.1; -; Genomic_DNA.
DR EMBL; AY086055; AAM63265.1; ALT_INIT; mRNA.
DR PIR; F86204; F86204.
DR RefSeq; NP_563774.1; NM_100572.3.
DR AlphaFoldDB; Q9LMJ3; -.
DR SMR; Q9LMJ3; -.
DR STRING; 3702.AT1G06990.1; -.
DR PaxDb; Q9LMJ3; -.
DR PRIDE; Q9LMJ3; -.
DR ProteomicsDB; 247086; -.
DR EnsemblPlants; AT1G06990.1; AT1G06990.1; AT1G06990.
DR GeneID; 837209; -.
DR Gramene; AT1G06990.1; AT1G06990.1; AT1G06990.
DR KEGG; ath:AT1G06990; -.
DR Araport; AT1G06990; -.
DR TAIR; locus:2007402; AT1G06990.
DR eggNOG; ENOG502QSNM; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; Q9LMJ3; -.
DR OMA; IQMTMAM; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9LMJ3; -.
DR BioCyc; ARA:AT1G06990-MON; -.
DR PRO; PR:Q9LMJ3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LMJ3; baseline and differential.
DR Genevisible; Q9LMJ3; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..360
FT /note="GDSL esterase/lipase At1g06990"
FT /id="PRO_0000367343"
FT ACT_SITE 44
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 335
FT /evidence="ECO:0000250"
FT ACT_SITE 338
FT /evidence="ECO:0000250"
FT CARBOHYD 26
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 31
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 73
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 126
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 272
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 306
FT /note="C -> S (in Ref. 3; AAM63265)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 360 AA; 39982 MW; 5481076DEC044E8B CRC64;
MLIHVIIFMI ITTMQFSTTC HAYVINVTNV NVSMFPAILV FGDSTIDTGN NNYIKTYIRA
NFPPYGCNFP GHNATGRFSN GKLIPDFIAS LMGIKDTVPP FLDPHLSDSD IITGVCFASA
GSGYDNLTDR ATSTLSVDKQ ADMLRSYVER LSQIVGDEKA ASIVSEALVI VSSGTNDFNL
NLYDTPSRRQ KLGVDGYQSF ILSNVHNFVQ ELYDIGCRKI MVLGLPPVGC LPIQMTMAMQ
KQNERRCIDK QNSDSQEFNQ KLKNSLTEMQ SNLTGSVIFY GDIYGALFDM ATNPQRYGLK
ETTRGCCGTG EIELAYLCNA LTRICPNPNQ YLFWDDIHPS QIAYIVISLS LVEQIFHVLS
