GDL23_ARATH
ID GDL23_ARATH Reviewed; 360 AA.
AC Q9C648; Q8LB77; Q9SM03;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=GDSL esterase/lipase At1g58430;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g58430;
DE Flags: Precursor;
GN OrderedLocusNames=At1g58430; ORFNames=F9K23.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=10548732; DOI=10.1016/s0378-1119(99)00403-5;
RA Kato A., Suzuki M., Kuwahara A., Ooe H., Higano-Inaba K., Komeda Y.;
RT "Isolation and analysis of cDNA within a 300 kb Arabidopsis thaliana
RT genomic region located around the 100 map unit of chromosome 1.";
RL Gene 239:309-316(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [6]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AB008020; BAA88267.1; -; mRNA.
DR EMBL; AB077822; BAB83874.1; -; Genomic_DNA.
DR EMBL; AC082643; AAG50646.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33548.1; -; Genomic_DNA.
DR EMBL; AY087373; AAM64923.1; -; mRNA.
DR PIR; B96618; B96618.
DR PIR; T52463; T52463.
DR RefSeq; NP_176139.1; NM_104623.3.
DR AlphaFoldDB; Q9C648; -.
DR SMR; Q9C648; -.
DR PaxDb; Q9C648; -.
DR PRIDE; Q9C648; -.
DR ProteomicsDB; 221969; -.
DR EnsemblPlants; AT1G58430.1; AT1G58430.1; AT1G58430.
DR GeneID; 842212; -.
DR Gramene; AT1G58430.1; AT1G58430.1; AT1G58430.
DR KEGG; ath:AT1G58430; -.
DR Araport; AT1G58430; -.
DR TAIR; locus:2037665; AT1G58430.
DR eggNOG; ENOG502QSNM; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; Q9C648; -.
DR OMA; FMCNAYS; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9C648; -.
DR BioCyc; ARA:AT1G58430-MON; -.
DR PRO; PR:Q9C648; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C648; baseline and differential.
DR Genevisible; Q9C648; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..360
FT /note="GDSL esterase/lipase At1g58430"
FT /id="PRO_0000367365"
FT ACT_SITE 42
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 334
FT /evidence="ECO:0000250"
FT ACT_SITE 337
FT /evidence="ECO:0000250"
FT CARBOHYD 22
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 104
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 326
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 11
FT /note="L -> F (in Ref. 4; AAM64923)"
FT /evidence="ECO:0000305"
FT CONFLICT 16
FT /note="T -> I (in Ref. 4; AAM64923)"
FT /evidence="ECO:0000305"
FT CONFLICT 19
FT /note="G -> A (in Ref. 4; AAM64923)"
FT /evidence="ECO:0000305"
FT CONFLICT 186
FT /note="S -> T (in Ref. 4; AAM64923)"
FT /evidence="ECO:0000305"
FT CONFLICT 203..204
FT /note="SR -> NK (in Ref. 4; AAM64923)"
FT /evidence="ECO:0000305"
FT CONFLICT 210
FT /note="K -> M (in Ref. 4; AAM64923)"
FT /evidence="ECO:0000305"
FT CONFLICT 314
FT /note="S -> N (in Ref. 1; BAA88267)"
FT /evidence="ECO:0000305"
FT CONFLICT 325
FT /note="Q -> E (in Ref. 4; AAM64923)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 360 AA; 40402 MW; 708CE6096A93619D CRC64;
MWTSKTISFT LFITTTLLGS CNASAKAKTQ PLFPAILIFG DSTVDTGNNN YPSQTIFRAK
HVPYGIDLPN HSPNGRFSNG KIFSDIIATK LNIKQFVPPF LQPNLTDQEI VTGVCFASAG
AGYDDQTSLT TQAIRVSEQP NMFKSYIARL KSIVGDKKAM KIINNALVVV SAGPNDFILN
YYEVPSWRRM YPSISDYQDF VLSRLNNFVK ELYSLGCRKI LVGGLPPMGC LPIQMTAQFR
NVLRFCLEQE NRDSVLYNQK LQKLLPQTQA SLTGSKILYS DVYDPMMEML QNPSKYGFKE
TTRGCCGTGF LETSFMCNAY SSMCQNRSEF LFFDSIHPSE ATYNYIGNVL DTKIRGWLKA
