GDL26_ARATH
ID GDL26_ARATH Reviewed; 349 AA.
AC F4IBF0; B3H492; Q93W97;
DT 16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2012, sequence version 2.
DT 25-MAY-2022, entry version 59.
DE RecName: Full=GDSL esterase/lipase At1g59030;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g59030;
DE Flags: Precursor;
GN OrderedLocusNames=At1g59030; ORFNames=T4M14.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC027036; AAK62791.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33568.2; -; Genomic_DNA.
DR RefSeq; NP_564738.3; NM_104633.3.
DR RefSeq; NP_564741.3; NM_104641.4.
DR RefSeq; NP_683444.2; NM_148603.3.
DR AlphaFoldDB; F4IBF0; -.
DR SMR; F4IBF0; -.
DR DNASU; 842238; -.
DR EnsemblPlants; AT1G58725.1; AT1G58725.1; AT1G58725.
DR EnsemblPlants; AT1G59030.1; AT1G59030.1; AT1G59030.
DR EnsemblPlants; AT1G59406.1; AT1G59406.1; AT1G59406.
DR GeneID; 842223; -.
DR GeneID; 842230; -.
DR GeneID; 842238; -.
DR Gramene; AT1G58725.1; AT1G58725.1; AT1G58725.
DR Gramene; AT1G59030.1; AT1G59030.1; AT1G59030.
DR Gramene; AT1G59406.1; AT1G59406.1; AT1G59406.
DR KEGG; ath:AT1G58725; -.
DR KEGG; ath:AT1G59030; -.
DR KEGG; ath:AT1G59406; -.
DR Araport; AT1G59030; -.
DR TAIR; locus:2827016; AT1G59030.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; F4IBF0; -.
DR OMA; FDMIQNP; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; F4IBF0; -.
DR PRO; PR:F4IBF0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR Genevisible; F4IBF0; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR008265; Lipase_GDSL_AS.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
DR PROSITE; PS01098; LIPASE_GDSL_SER; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..349
FT /note="GDSL esterase/lipase At1g59030"
FT /id="PRO_0000367368"
FT ACT_SITE 37
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 324
FT /evidence="ECO:0000250"
FT ACT_SITE 327
FT /evidence="ECO:0000250"
FT CARBOHYD 25
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 316
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 349 AA; 38858 MW; 40DC04462C16C23C CRC64;
MKIQILLFAL VLIFVEANAA TQGKNTTIPA LIVFGDSIMD TGNNNNLPTL LKCNFPPYGK
DYPGGFATGR FSDGRVPSDL IAEKLGLAKT LPAYMNPYLK PEDLLKGVTF ASGGTGYDPL
TAKIMSVISV WDQLINFKEY ISKIKRHFGE EKAKDILEHS FFLVVSSSND LAHTYLAQTH
RYDRTSYANF LADSAVHFVR ELHKLGARKI GVFSAVPVGC VPLQRTVFGG FFTRGCNQPL
NNMAKQFNAR LSPALDSLDK ELDGVILYIN VYDTLFDMIQ HPKKYGFEVA DRGCCGKGLL
AISYLCNSLN PFTCSNSSAY IFWDSYHPSE RAYQVIVDNL LDKYLSKVY
