GDL28_ARATH
ID GDL28_ARATH Reviewed; 374 AA.
AC Q9FVV1;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=GDSL esterase/lipase At1g71250;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g71250;
DE Flags: Precursor;
GN OrderedLocusNames=At1g71250; ORFNames=F3I17.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [6]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC016162; AAG51891.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35180.1; -; Genomic_DNA.
DR EMBL; AK117368; BAC42038.1; -; mRNA.
DR EMBL; BT005325; AAO63389.1; -; mRNA.
DR PIR; B96737; B96737.
DR RefSeq; NP_177281.1; NM_105794.4.
DR AlphaFoldDB; Q9FVV1; -.
DR SMR; Q9FVV1; -.
DR STRING; 3702.AT1G71250.1; -.
DR PaxDb; Q9FVV1; -.
DR PRIDE; Q9FVV1; -.
DR ProteomicsDB; 224752; -.
DR EnsemblPlants; AT1G71250.1; AT1G71250.1; AT1G71250.
DR GeneID; 843466; -.
DR Gramene; AT1G71250.1; AT1G71250.1; AT1G71250.
DR KEGG; ath:AT1G71250; -.
DR Araport; AT1G71250; -.
DR TAIR; locus:2032333; AT1G71250.
DR eggNOG; ENOG502QQWI; Eukaryota.
DR HOGENOM; CLU_015101_0_0_1; -.
DR InParanoid; Q9FVV1; -.
DR OMA; NQMLGSF; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9FVV1; -.
DR BioCyc; ARA:AT1G71250-MON; -.
DR PRO; PR:Q9FVV1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FVV1; baseline and differential.
DR Genevisible; Q9FVV1; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR008265; Lipase_GDSL_AS.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
DR PROSITE; PS01098; LIPASE_GDSL_SER; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..374
FT /note="GDSL esterase/lipase At1g71250"
FT /id="PRO_0000367369"
FT ACT_SITE 48
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 338
FT /evidence="ECO:0000250"
FT ACT_SITE 341
FT /evidence="ECO:0000250"
FT CARBOHYD 162
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 374 AA; 41192 MW; D0D4E4A547DB8EFC CRC64;
MNTNRKKMKV HIGGYVLILA LTVSVILQQP ELVTGQARVP AMFVLGDSLV DAGNNNFLQT
VARANFLPYG IDMNYQPTGR FSNGLTFIDL LARLLEIPSP PPFADPTTSG NRILQGVNYA
SAAAGILDVS GYNYGGRFSL NQQMVNLETT LSQLRTMMSP QNFTDYLARS LVVLVFGSND
YINNYLMPNL YDSSIRFRPP DFANLLLSQY ARQLLTLYSL GLRKIFIPGV APLGCIPNQR
ARGISPPDRC VDSVNQILGT FNQGLKSLVD QLNQRSPGAI YVYGNTYSAI GDILNNPAAY
GFSVVDRACC GIGRNQGQIT CLPLQTPCPN RNQYVFWDAF HPTQTANSIL ARRAFYGPPS
DAYPVNVQQM TLLH
