GDL29_ARATH
ID GDL29_ARATH Reviewed; 384 AA.
AC Q9SF78; Q3ECE0;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=GDSL esterase/lipase At1g71691;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g71691;
DE Flags: Precursor;
GN OrderedLocusNames=At1g71691; ORFNames=F14O23.4, F26A9.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9SF78-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9SF78-2; Sequence=VSP_036694;
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BX817660; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AC012654; AAF43219.1; -; Genomic_DNA.
DR EMBL; AC016163; AAG51812.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35214.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35215.1; -; Genomic_DNA.
DR EMBL; BX817660; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; G96738; G96738.
DR RefSeq; NP_565021.2; NM_105824.4. [Q9SF78-2]
DR RefSeq; NP_974125.1; NM_202396.3. [Q9SF78-1]
DR AlphaFoldDB; Q9SF78; -.
DR SMR; Q9SF78; -.
DR STRING; 3702.AT1G71691.2; -.
DR PaxDb; Q9SF78; -.
DR PRIDE; Q9SF78; -.
DR ProteomicsDB; 247088; -. [Q9SF78-1]
DR EnsemblPlants; AT1G71691.1; AT1G71691.1; AT1G71691. [Q9SF78-2]
DR EnsemblPlants; AT1G71691.2; AT1G71691.2; AT1G71691. [Q9SF78-1]
DR GeneID; 843496; -.
DR Gramene; AT1G71691.1; AT1G71691.1; AT1G71691. [Q9SF78-2]
DR Gramene; AT1G71691.2; AT1G71691.2; AT1G71691. [Q9SF78-1]
DR KEGG; ath:AT1G71691; -.
DR Araport; AT1G71691; -.
DR TAIR; locus:2824531; AT1G71691.
DR eggNOG; ENOG502QUVY; Eukaryota.
DR HOGENOM; CLU_015101_0_0_1; -.
DR InParanoid; Q9SF78; -.
DR OMA; AKCIFFV; -.
DR PhylomeDB; Q9SF78; -.
DR BioCyc; ARA:AT1G71691-MON; -.
DR PRO; PR:Q9SF78; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SF78; baseline and differential.
DR Genevisible; Q9SF78; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..384
FT /note="GDSL esterase/lipase At1g71691"
FT /id="PRO_0000367370"
FT ACT_SITE 62
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 348
FT /evidence="ECO:0000250"
FT ACT_SITE 351
FT /evidence="ECO:0000250"
FT VAR_SEQ 1..106
FT /note="MAFHFRRLCFFSALLAVVLQLLHGVSGQLVVVEEPISAPPPPLVDLNTGDGI
FT VPALFVFGDSLIDNGNNNNIPSFAKANYFPYGIDFNGGPTGRFCNGLTMVDGIA -> M
FT GLVT (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_036694"
SQ SEQUENCE 384 AA; 41725 MW; 87E3F7FED747E13D CRC64;
MAFHFRRLCF FSALLAVVLQ LLHGVSGQLV VVEEPISAPP PPLVDLNTGD GIVPALFVFG
DSLIDNGNNN NIPSFAKANY FPYGIDFNGG PTGRFCNGLT MVDGIAQLLG LPLIPAYSEA
TGDQVLRGVN YASAAAGILP DTGGNFVGRI PFDQQIHNFE TTLDQVASKS GGAVAIADSV
TRSLFFIGMG SNDYLNNYLM PNFPTRNQYN SQQFGDLLVQ HYTDQLTRLY NLGGRKFVVA
GLGRMGCIPS ILAQGNDGKC SEEVNQLVLP FNTNVKTMIS NLNQNLPDAK FIYLDIAHMF
EDIVANQAAY GLTTMDKGCC GIGKNRGQIT CLPFETPCPN RDQYVFWDAF HPTEKVNLIM
AKKAFAGDRT VAYPINIQQL ASLN
