GDL30_ARATH
ID GDL30_ARATH Reviewed; 344 AA.
AC Q9C9V0;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=GDSL esterase/lipase At1g73610;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g73610;
DE Flags: Precursor;
GN OrderedLocusNames=At1g73610; ORFNames=F25P22.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC012679; AAG52082.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35485.1; -; Genomic_DNA.
DR PIR; A96763; A96763.
DR RefSeq; NP_177502.1; NM_106019.2.
DR AlphaFoldDB; Q9C9V0; -.
DR SMR; Q9C9V0; -.
DR PaxDb; Q9C9V0; -.
DR PRIDE; Q9C9V0; -.
DR ProteomicsDB; 224753; -.
DR EnsemblPlants; AT1G73610.1; AT1G73610.1; AT1G73610.
DR GeneID; 843695; -.
DR Gramene; AT1G73610.1; AT1G73610.1; AT1G73610.
DR KEGG; ath:AT1G73610; -.
DR Araport; AT1G73610; -.
DR TAIR; locus:2027839; AT1G73610.
DR eggNOG; ENOG502R6GS; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; Q9C9V0; -.
DR OMA; ATFPGAK; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9C9V0; -.
DR BioCyc; ARA:AT1G73610-MON; -.
DR PRO; PR:Q9C9V0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C9V0; baseline and differential.
DR Genevisible; Q9C9V0; AT.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR008265; Lipase_GDSL_AS.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
DR PROSITE; PS01098; LIPASE_GDSL_SER; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..344
FT /note="GDSL esterase/lipase At1g73610"
FT /id="PRO_0000367371"
FT ACT_SITE 42
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 319
FT /evidence="ECO:0000250"
FT ACT_SITE 322
FT /evidence="ECO:0000250"
FT CARBOHYD 30
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 344 AA; 37503 MW; BCEB6475E2C96400 CRC64;
MNCLMFFKML LAFSFISLFY VGNAQQSYGN STVSALFAFG DSILDTGNNN LLLSVSKVNF
YPYGRDFIGG RATGRFGNGR VFSDIIAEGL GLKNLLPAYR DPYLWNNDLT TGVCFASGGS
GLDPITARTT GSIWVSDQVT DFQNYITRLN GVVGNQEQAN AVISNAVYLI SAGNNDIAIT
YFTTGARRLQ YTLPAYNDQL VSWTRDLIKS LYDMGARKFA VMGTLPLGCL PGARALTRAC
ELFVNQGAAM FNQQLSADID NLGATFPGAK FVYVDMYNPL LGLIINPQAS GFIDVADACC
CTPTHLIPCL DASRYVFWDV AHPTQKSYET IAPQIIENIK AKLA
