GDL34_ARATH
ID GDL34_ARATH Reviewed; 350 AA.
AC Q9SJB4; Q682P3; Q8LAB2;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=GDSL esterase/lipase At2g04570;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At2g04570;
DE Flags: Precursor;
GN OrderedLocusNames=At2g04570; ORFNames=T1O3.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [6]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC006951; AAD25823.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05848.1; -; Genomic_DNA.
DR EMBL; AK175324; BAD43087.1; -; mRNA.
DR EMBL; AY087937; AAM65485.1; -; mRNA.
DR PIR; A84459; A84459.
DR RefSeq; NP_178536.1; NM_126488.3.
DR AlphaFoldDB; Q9SJB4; -.
DR SMR; Q9SJB4; -.
DR STRING; 3702.AT2G04570.1; -.
DR PaxDb; Q9SJB4; -.
DR PRIDE; Q9SJB4; -.
DR ProteomicsDB; 224755; -.
DR EnsemblPlants; AT2G04570.1; AT2G04570.1; AT2G04570.
DR GeneID; 814999; -.
DR Gramene; AT2G04570.1; AT2G04570.1; AT2G04570.
DR KEGG; ath:AT2G04570; -.
DR Araport; AT2G04570; -.
DR TAIR; locus:2058309; AT2G04570.
DR eggNOG; ENOG502QQ8I; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; Q9SJB4; -.
DR OMA; SQYTIDQ; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9SJB4; -.
DR BioCyc; ARA:AT2G04570-MON; -.
DR PRO; PR:Q9SJB4; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SJB4; baseline and differential.
DR Genevisible; Q9SJB4; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016297; F:acyl-[acyl-carrier-protein] hydrolase activity; IDA:TAIR.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..350
FT /note="GDSL esterase/lipase At2g04570"
FT /id="PRO_0000367375"
FT ACT_SITE 35
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 325
FT /evidence="ECO:0000250"
FT ACT_SITE 328
FT /evidence="ECO:0000250"
FT CARBOHYD 98
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 117
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 343
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 151
FT /note="G -> A (in Ref. 4; AAM65485)"
FT /evidence="ECO:0000305"
FT CONFLICT 175
FT /note="A -> V (in Ref. 4; AAM65485)"
FT /evidence="ECO:0000305"
FT CONFLICT 259
FT /note="S -> N (in Ref. 4; AAM65485)"
FT /evidence="ECO:0000305"
FT CONFLICT 345
FT /note="T -> I (in Ref. 3; BAD43087)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 350 AA; 38478 MW; C2D077E9A8D59842 CRC64;
MGHLKSLFTI LFLIAMSSTV TFAGKIPAII VFGDSSVDAG NNNYIPTVAR SNFEPYGRDF
VGGKPTGRFC NGKIATDFMS EALGLKPIIP AYLDPSYNIS DFATGVTFAS AATGYDNATS
DVLSVLPLWK QLEYYKEYQT KLKAYQGKDR GTETIESSLY LISIGTNDFL ENYFAFPGRS
SQYSVSLYQD FLAGIAKEFV KKLHGLGARK ISLGGLPPMG CMPLERATNI GTGGECVGRY
NDIAVQFNSK LDKMVEKLSK ELPGSNLVFS NPYEPFMRII KNPSSFGFEV VGAACCATGM
FEMGYGCQRN NPFTCTNADK YVFWDSFHPT QKTNHIMANA LMNSTFPHFL
