GDL36_ARATH
ID GDL36_ARATH Reviewed; 349 AA.
AC O64468;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=GDSL esterase/lipase At2g19050;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At2g19050;
DE Flags: Precursor;
GN OrderedLocusNames=At2g19050; ORFNames=T20K24.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC002392; AAD12023.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06843.1; -; Genomic_DNA.
DR PIR; T00525; T00525.
DR RefSeq; NP_179495.1; NM_127462.2.
DR AlphaFoldDB; O64468; -.
DR SMR; O64468; -.
DR STRING; 3702.AT2G19050.1; -.
DR PaxDb; O64468; -.
DR PRIDE; O64468; -.
DR ProteomicsDB; 221973; -.
DR EnsemblPlants; AT2G19050.1; AT2G19050.1; AT2G19050.
DR GeneID; 816422; -.
DR Gramene; AT2G19050.1; AT2G19050.1; AT2G19050.
DR KEGG; ath:AT2G19050; -.
DR Araport; AT2G19050; -.
DR TAIR; locus:2059078; AT2G19050.
DR eggNOG; ENOG502SIA8; Eukaryota.
DR HOGENOM; CLU_015101_0_0_1; -.
DR InParanoid; O64468; -.
DR OMA; PTEAWNE; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; O64468; -.
DR BioCyc; ARA:AT2G19050-MON; -.
DR PRO; PR:O64468; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O64468; baseline and differential.
DR Genevisible; O64468; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..349
FT /note="GDSL esterase/lipase At2g19050"
FT /id="PRO_0000367377"
FT ACT_SITE 38
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 316
FT /evidence="ECO:0000250"
FT ACT_SITE 319
FT /evidence="ECO:0000250"
FT CARBOHYD 49
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 349 AA; 38577 MW; 05DAC363EA5F3D2A CRC64;
MAEAIFKALL LVIATTAFAT TEAALGQRVP CYFVFGDSVF DNGNNNVLNT SAKVNYSPYG
IDFARGPTGR FSNGRNIPDI IAELMRFSDY IPPFTGASPE QAHIGINYAS GGGGIREETS
QHLGEIISFK KQIKNHRSMI MTAKVPEEKL NKCLYTINIG SNDYLNNYFM PAPYMTNKKF
SFDEYADSLI RSYRSYLKSL YVLGARKVAV FGVSKLGCTP RMIASHGGGN GCAAEVNKAV
EPFNKNLKAL VYEFNRDFAD AKFTFVDIFS GQSPFAFFML GFRVTDKSCC TVKPGEELCA
TNEPVCPVQR RYVYWDNVHS TEAANMVVAK AAYAGLITSP YSLSWLARL
