GDL38_ARATH
ID GDL38_ARATH Reviewed; 387 AA.
AC O80470;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=GDSL esterase/lipase At2g23540;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At2g23540;
DE Flags: Precursor;
GN OrderedLocusNames=At2g23540; ORFNames=F26B6.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC003040; AAC23769.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07463.1; -; Genomic_DNA.
DR EMBL; AY099614; AAM20465.1; -; mRNA.
DR EMBL; AY128861; AAM91261.1; -; mRNA.
DR PIR; T01143; T01143.
DR RefSeq; NP_179935.1; NM_127918.4.
DR AlphaFoldDB; O80470; -.
DR SMR; O80470; -.
DR STRING; 3702.AT2G23540.1; -.
DR PaxDb; O80470; -.
DR PRIDE; O80470; -.
DR ProteomicsDB; 221975; -.
DR EnsemblPlants; AT2G23540.1; AT2G23540.1; AT2G23540.
DR GeneID; 816886; -.
DR Gramene; AT2G23540.1; AT2G23540.1; AT2G23540.
DR KEGG; ath:AT2G23540; -.
DR Araport; AT2G23540; -.
DR TAIR; locus:2046743; AT2G23540.
DR eggNOG; ENOG502QTV6; Eukaryota.
DR HOGENOM; CLU_015101_0_0_1; -.
DR InParanoid; O80470; -.
DR OMA; PKYISPM; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; O80470; -.
DR BioCyc; ARA:AT2G23540-MON; -.
DR PRO; PR:O80470; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O80470; baseline and differential.
DR Genevisible; O80470; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..32
FT /evidence="ECO:0000255"
FT CHAIN 33..387
FT /note="GDSL esterase/lipase At2g23540"
FT /id="PRO_0000367379"
FT ACT_SITE 55
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 352
FT /evidence="ECO:0000250"
FT ACT_SITE 355
FT /evidence="ECO:0000250"
FT CARBOHYD 139
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 159
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 380
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 387 AA; 42083 MW; 1E26C65AD3CBDD16 CRC64;
MATRASTSSR VSPAFTFLVI FFLLSLTASV EAAGRGVNND KKGGGLGASF IFGDSLVDAG
NNNYLSTLSR ANMKPNGIDF KASGGTPTGR FTNGRTIGDI VGEELGSANY AIPFLAPDAK
GKALLAGVNY ASGGGGIMNA TGRIFVNRLG MDVQVDFFNT TRKQFDDLLG KEKAKDYIAK
KSIFSITIGA NDFLNNYLFP LLSVGTRFTQ TPDDFIGDML EHLRDQLTRL YQLDARKFVI
GNVGPIGCIP YQKTINQLDE NECVDLANKL ANQYNVRLKS LLEELNKKLP GAMFVHANVY
DLVMELITNY DKYGFKSATK ACCGNGGQYA GIIPCGPTSS LCEERDKYVF WDPYHPSEAA
NVIIAKQLLY GDVKVISPVN LSKLRDM
