GDL41_ARATH
ID GDL41_ARATH Reviewed; 358 AA.
AC O22918;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=GDSL esterase/lipase At2g30220;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At2g30220;
DE Flags: Precursor;
GN OrderedLocusNames=At2g30220; ORFNames=T9D9.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC002338; AAC16946.1; -; Genomic_DNA.
DR EMBL; AC004165; AAM14915.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08359.1; -; Genomic_DNA.
DR PIR; T00578; T00578.
DR RefSeq; NP_180581.1; NM_128575.2.
DR AlphaFoldDB; O22918; -.
DR SMR; O22918; -.
DR PaxDb; O22918; -.
DR PRIDE; O22918; -.
DR ProteomicsDB; 224757; -.
DR EnsemblPlants; AT2G30220.1; AT2G30220.1; AT2G30220.
DR GeneID; 817572; -.
DR Gramene; AT2G30220.1; AT2G30220.1; AT2G30220.
DR KEGG; ath:AT2G30220; -.
DR Araport; AT2G30220; -.
DR TAIR; locus:2060869; AT2G30220.
DR eggNOG; ENOG502QSNM; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; O22918; -.
DR OMA; ICVEQEN; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; O22918; -.
DR BioCyc; ARA:AT2G30220-MON; -.
DR PRO; PR:O22918; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22918; baseline and differential.
DR Genevisible; O22918; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..358
FT /note="GDSL esterase/lipase At2g30220"
FT /id="PRO_0000367382"
FT ACT_SITE 40
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 332
FT /evidence="ECO:0000250"
FT ACT_SITE 335
FT /evidence="ECO:0000250"
FT CARBOHYD 25
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 102
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 324
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 358 AA; 39672 MW; 3A781CCFED165F49 CRC64;
MYISKTIVFG LFVATLLVSC NADANTTQPL FPAILIFGDS TADTGNNNYY SQAVFKANHL
PYGVDLPGHE ANGRFSNGKL ISDVISTKLN IKEFVPPFLQ PNISDQDIVT GVCFASAGAG
YDDETSLSSK AIPVSQQPSM FKNYIARLKG IVGDKKAMEI INNALVVISA GPNDFILNFY
DIPIRRLEYP TIYGYQDFVL KRLDGFVREL YSLGCRNILV GGLPPMGCLP IQLTAKLRTI
LGICVEQENK DSILYNQKLV KKLPEIQASL PGSKFLYANV YDPVMDMIRN PSKYGFKETK
KGCCGTGYLE TSFLCTSLSK TCPNHSDHLF WDSIHPSEAA YKYLGNFIDA QIQEWLKT
