GDL42_ARATH
ID GDL42_ARATH Reviewed; 359 AA.
AC O22927;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=GDSL esterase/lipase At2g30310;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At2g30310;
DE Flags: Precursor;
GN OrderedLocusNames=At2g30310; ORFNames=T9D9.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC002338; AAC16947.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08369.1; -; Genomic_DNA.
DR EMBL; DQ056555; AAY78705.1; -; mRNA.
DR PIR; H84706; H84706.
DR RefSeq; NP_180590.1; NM_128584.2.
DR AlphaFoldDB; O22927; -.
DR SMR; O22927; -.
DR PaxDb; O22927; -.
DR PRIDE; O22927; -.
DR ProteomicsDB; 221976; -.
DR EnsemblPlants; AT2G30310.1; AT2G30310.1; AT2G30310.
DR GeneID; 817581; -.
DR Gramene; AT2G30310.1; AT2G30310.1; AT2G30310.
DR KEGG; ath:AT2G30310; -.
DR Araport; AT2G30310; -.
DR TAIR; locus:2065737; AT2G30310.
DR eggNOG; ENOG502QSNM; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; O22927; -.
DR OMA; TESTYYK; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; O22927; -.
DR BioCyc; ARA:AT2G30310-MON; -.
DR PRO; PR:O22927; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22927; baseline and differential.
DR Genevisible; O22927; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..359
FT /note="GDSL esterase/lipase At2g30310"
FT /id="PRO_0000367383"
FT ACT_SITE 41
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 333
FT /evidence="ECO:0000250"
FT ACT_SITE 336
FT /evidence="ECO:0000250"
FT CARBOHYD 103
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 325
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 359 AA; 39739 MW; CB50B7E3BF0E2F90 CRC64;
MSTSKTIVFG LFVATLLVSC NVAANATTQP LFPAILIFGD STVDTGNNNY HSQTIFKAKH
LPYGVDLPGH EANGRYSNGK VISDVIASKL NIKELVPPFL QPNISHQDIV TGVSFASAGA
GYDDRSSLSS KAIPVSQQPS MFKNYIARLK GIVGDKKAME IINNALVVIS AGPNDFILNF
YDIPTRRLEY PTIHGYQEFI LKRLDGFVRE LYSLGCRNIV VGGLPPMGCL PIQMTAKMRN
ILRFCVEQEN KDSVLYNQKL VKKLPEIQAS LPGSNFLYAN VYDPLMDMIQ NPSKYGFKET
KKGCCGTGYL ETTFMCNPLT KTCPNHSDHL FWDSIHPSEA AYNYIGNFVD AQIRGWIKA
