GDL43_ARATH
ID GDL43_ARATH Reviewed; 360 AA.
AC Q9SIQ3; Q8LFE6;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=GDSL esterase/lipase At2g31540;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At2g31540;
DE Flags: Precursor;
GN OrderedLocusNames=At2g31540; ORFNames=T9H9.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC007071; AAD24833.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08558.1; -; Genomic_DNA.
DR EMBL; AY084895; AAM61458.1; -; mRNA.
DR PIR; A84722; A84722.
DR RefSeq; NP_180712.1; NM_128711.2.
DR AlphaFoldDB; Q9SIQ3; -.
DR SMR; Q9SIQ3; -.
DR PaxDb; Q9SIQ3; -.
DR PRIDE; Q9SIQ3; -.
DR ProteomicsDB; 247093; -.
DR EnsemblPlants; AT2G31540.1; AT2G31540.1; AT2G31540.
DR GeneID; 817712; -.
DR Gramene; AT2G31540.1; AT2G31540.1; AT2G31540.
DR KEGG; ath:AT2G31540; -.
DR Araport; AT2G31540; -.
DR TAIR; locus:2065883; AT2G31540.
DR eggNOG; ENOG502QSNM; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; Q9SIQ3; -.
DR OMA; FTHYYRS; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9SIQ3; -.
DR BioCyc; ARA:AT2G31540-MON; -.
DR PRO; PR:Q9SIQ3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIQ3; baseline and differential.
DR Genevisible; Q9SIQ3; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..360
FT /note="GDSL esterase/lipase At2g31540"
FT /id="PRO_0000367384"
FT ACT_SITE 42
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 334
FT /evidence="ECO:0000250"
FT ACT_SITE 337
FT /evidence="ECO:0000250"
FT CARBOHYD 104
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 326
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 25
FT /note="A -> T (in Ref. 3; AAM61458)"
FT /evidence="ECO:0000305"
FT CONFLICT 314
FT /note="S -> G (in Ref. 3; AAM61458)"
FT /evidence="ECO:0000305"
FT CONFLICT 331
FT /note="L -> M (in Ref. 3; AAM61458)"
FT /evidence="ECO:0000305"
FT CONFLICT 349
FT /note="L -> R (in Ref. 3; AAM61458)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 360 AA; 40121 MW; FB01443FB79BC626 CRC64;
MSTSKAITLT LFIATTLLAP CNAAANATTK PLFPAILIFG DSTVDTGNNN YPLPTIFRAE
HFPYGMDLPD GKANGRFSNG KLISDIIATK LNIKEFIPPF LQPNLSDQDI LTGVCFASAG
AGYDDLTSLS TQAIRVSEQP NMFKSYIARL KGIVGDKKAM EIINNAFVVV SAGPNDFILN
YYEIPSRRLE YPFISGYQDF ILKRLENFVR ELYSLGVRNV LVGGLPPMGC LPIHMTAKFR
NIFRFCLEHH NKDSVLYNEK LQNLLPQIEA SLPGSKFLYA DVYNPMMEMI QNPSKYGFKE
TKRGCCGTGF LETSFMCNVF SPVCQNRSEF LFFDSIHPSE ATYNVIGNLL DPLIRGKFQA
