GDL45_ARATH
ID GDL45_ARATH Reviewed; 356 AA.
AC Q8RWJ4; Q9SJM5;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 2.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=GDSL esterase/lipase At2g36325;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At2g36325;
DE Flags: Precursor;
GN OrderedLocusNames=At2g36325; ORFNames=F2H17.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [6]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD21433.1; Type=Erroneous gene model prediction; Note=The predicted gene At2g36330 has been split into 2 genes: At2g36325 and At2g36330.; Evidence={ECO:0000305};
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DR EMBL; AC006921; AAD21433.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC09233.1; -; Genomic_DNA.
DR EMBL; AY093048; AAM13047.1; -; mRNA.
DR EMBL; AY128930; AAM91330.1; -; mRNA.
DR EMBL; AK221676; BAD95367.1; -; mRNA.
DR RefSeq; NP_001078012.1; NM_001084543.2.
DR AlphaFoldDB; Q8RWJ4; -.
DR SMR; Q8RWJ4; -.
DR iPTMnet; Q8RWJ4; -.
DR PaxDb; Q8RWJ4; -.
DR PRIDE; Q8RWJ4; -.
DR ProteomicsDB; 221977; -.
DR EnsemblPlants; AT2G36325.1; AT2G36325.1; AT2G36325.
DR GeneID; 5007939; -.
DR Gramene; AT2G36325.1; AT2G36325.1; AT2G36325.
DR KEGG; ath:AT2G36325; -.
DR Araport; AT2G36325; -.
DR TAIR; locus:4010713686; AT2G36325.
DR eggNOG; ENOG502QU3Y; Eukaryota.
DR HOGENOM; CLU_015101_2_1_1; -.
DR InParanoid; Q8RWJ4; -.
DR OMA; CTPSYTR; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q8RWJ4; -.
DR PRO; PR:Q8RWJ4; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8RWJ4; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0099503; C:secretory vesicle; HDA:TAIR.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..356
FT /note="GDSL esterase/lipase At2g36325"
FT /id="PRO_0000367386"
FT ACT_SITE 54
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 334
FT /evidence="ECO:0000250"
FT ACT_SITE 337
FT /evidence="ECO:0000250"
FT CARBOHYD 25
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 165
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 185
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 240
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 129
FT /note="G -> E (in Ref. 3; AAM13047/AAM91330 and 4;
FT BAD95367)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 356 AA; 39959 MW; F3D492ADB12C9948 CRC64;
MNITKLTPWF LFSCLILLSD YIKVNSSISP SSEQTQEDGF FGFKPTKLFV FGDSYADTGN
TPFLIVPSWR FPNGITFPGI PTGRFSDGRV STDYLAKYIG VRTPITYKWG KYGRPRLAVK
RGMNFAYGGA GAFETMFKLV PTASVQIDSF EQLLMRNVYS PADLNSSVAF FSIIGNDYLT
YDRRNGSEEG RSALTRKVVK QILLDVKRIK DLGVRKVLVA LSPPQKCLPK LVTPKGCDTN
DTSTYLHNSL LRKGLIKLND KEINNNDKSF MTLDLYNAFV TIFKNKGVSG VSTFPDPFKA
CCATKRGTFC GDRSLSGKKL YTLCDDPKSF FFWDNVHISD QGWRSVFSLL LPDSQF
