GDL47_ARATH
ID GDL47_ARATH Reviewed; 361 AA.
AC Q9SIZ6; Q9SYT1;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=GDSL esterase/lipase At2g40250;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At2g40250;
DE Flags: Precursor;
GN OrderedLocusNames=At2g40250; ORFNames=T07M07.13, T3G21;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10207155;
RA Wang M.L., Belmonte S., Kim U., Dolan M., Morris J.W., Goodman H.M.;
RT "A cluster of ABA-regulated genes on Arabidopsis thaliana BAC T07M07.";
RL Genome Res. 9:325-333(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [5]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [6]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD25940.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AF085279; AAD25940.1; ALT_INIT; Genomic_DNA.
DR EMBL; AC007020; AAD25660.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09802.1; -; Genomic_DNA.
DR EMBL; DQ056573; AAY78723.1; -; mRNA.
DR PIR; B84827; B84827.
DR RefSeq; NP_181554.1; NM_129583.2.
DR AlphaFoldDB; Q9SIZ6; -.
DR SMR; Q9SIZ6; -.
DR STRING; 3702.AT2G40250.1; -.
DR PaxDb; Q9SIZ6; -.
DR PRIDE; Q9SIZ6; -.
DR ProteomicsDB; 247096; -.
DR EnsemblPlants; AT2G40250.1; AT2G40250.1; AT2G40250.
DR GeneID; 818617; -.
DR Gramene; AT2G40250.1; AT2G40250.1; AT2G40250.
DR KEGG; ath:AT2G40250; -.
DR Araport; AT2G40250; -.
DR TAIR; locus:2063083; AT2G40250.
DR eggNOG; ENOG502QTDW; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR OMA; HEGCCGT; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9SIZ6; -.
DR BioCyc; ARA:AT2G40250-MON; -.
DR PRO; PR:Q9SIZ6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIZ6; baseline and differential.
DR Genevisible; Q9SIZ6; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Hydrolase; Lipid degradation; Lipid metabolism; Reference proteome;
KW Secreted; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..361
FT /note="GDSL esterase/lipase At2g40250"
FT /id="PRO_0000367388"
FT ACT_SITE 43
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 337
FT /evidence="ECO:0000250"
FT ACT_SITE 340
FT /evidence="ECO:0000250"
SQ SEQUENCE 361 AA; 39885 MW; 508A861F1FAF9F79 CRC64;
MNRNQHKPMF VTFLINILLL QLLNLTNASP SPPITALYAF GDSTVDSGNN NYIPTLFQSN
HPPYGKSFPS KLSTGRFSDG KLATDFIVSS LGLKPTLPAY LNPSVKPVDL LTGVSFASAG
GGLDDRTAKS SLTITMDKQW SYFEEALGKM KSLVGDSETN RVIKNAVFVI SAGTNDMIFN
VYDHVLGSLI SVSDYQDSLL TKVEVFVQRL YEAGARRITI AGLPPIGCLP VQVTLTSINT
PRIFHHRICT EHQNDDSRVY NQKLQKLIFG LSQRFRGSKV LYLDIYSPLI DMIKHPRKYG
LEETLRGCCG TGLLEAGPLC QPLSRTCDDV SKYLFFDSVH PSQTAYSVIA SFALQKLFPL
L
