GDL48_ARATH
ID GDL48_ARATH Reviewed; 350 AA.
AC Q67ZI9; Q67ZI0; Q9SJG0;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=GDSL esterase/lipase At2g42990;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At2g42990;
DE Flags: Precursor;
GN OrderedLocusNames=At2g42990; ORFNames=F23E6.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 48-350.
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [6]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD21711.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAM15290.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC006580; AAM15290.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC006931; AAD21711.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC10195.1; -; Genomic_DNA.
DR EMBL; AK175715; BAD43478.1; -; mRNA.
DR EMBL; AK176128; BAD43891.1; -; mRNA.
DR EMBL; AK176137; BAD43900.1; -; mRNA.
DR EMBL; BT011672; AAS47678.1; -; mRNA.
DR PIR; F84860; F84860.
DR RefSeq; NP_181827.2; NM_129860.4.
DR AlphaFoldDB; Q67ZI9; -.
DR SMR; Q67ZI9; -.
DR STRING; 3702.AT2G42990.1; -.
DR PaxDb; Q67ZI9; -.
DR PRIDE; Q67ZI9; -.
DR ProteomicsDB; 224758; -.
DR EnsemblPlants; AT2G42990.1; AT2G42990.1; AT2G42990.
DR GeneID; 818901; -.
DR Gramene; AT2G42990.1; AT2G42990.1; AT2G42990.
DR KEGG; ath:AT2G42990; -.
DR Araport; AT2G42990; -.
DR TAIR; locus:2045610; AT2G42990.
DR eggNOG; ENOG502QXBZ; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; Q67ZI9; -.
DR OMA; EMSFLCN; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q67ZI9; -.
DR BioCyc; ARA:AT2G42990-MON; -.
DR PRO; PR:Q67ZI9; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q67ZI9; baseline and differential.
DR Genevisible; Q67ZI9; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..350
FT /note="GDSL esterase/lipase At2g42990"
FT /id="PRO_0000367389"
FT ACT_SITE 35
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 325
FT /evidence="ECO:0000250"
FT ACT_SITE 328
FT /evidence="ECO:0000250"
FT CARBOHYD 98
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 117
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 141
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 350 AA; 39200 MW; 56BF44187003284E CRC64;
MATHYLSPSI LCIILTTLVS IAGAKIPAII VFGDSSVDSG NNNFISTMAR ANFEPYGRDF
PGGRATGRFC NGRLSSDFTS EAYGLKPTVP AYLDPSYNIS DFATGVCFAS AGTGYDNSTA
DVLGVIPLWK EVEYFKEYQS NLSAYLGHRR AAKIIRESLY IVSIGTNDFL ENYYTLPDRR
SQFSISQYQD FLVEIAEVFL KDIYRLGARK MSFTGISPMG CLPLERVTNL DDPFSCARSY
NDLAVDFNGR LRRLVTKLNR ELTGIKIYFA NPYDIMWDIV TKPNLYGLEI SSSACCGTGL
FEMGFLCGQD NPLTCSDANK FVFWDAFHPT ERTNQIVSDH FFKHLKNLFH
