GDL55_ARATH
ID GDL55_ARATH Reviewed; 288 AA.
AC Q3EAQ9; Q1PEJ2; Q9M235;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=GDSL esterase/lipase At3g43550;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At3g43550;
DE Flags: Precursor;
GN OrderedLocusNames=At3g43550; ORFNames=T18D12.120;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB81795.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL138644; CAB81795.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE77805.1; -; Genomic_DNA.
DR EMBL; DQ446726; ABE65987.1; -; mRNA.
DR PIR; T47397; T47397.
DR RefSeq; NP_189941.3; NM_114223.3.
DR AlphaFoldDB; Q3EAQ9; -.
DR SMR; Q3EAQ9; -.
DR STRING; 3702.AT3G43550.1; -.
DR PaxDb; Q3EAQ9; -.
DR PRIDE; Q3EAQ9; -.
DR ProteomicsDB; 221979; -.
DR EnsemblPlants; AT3G43550.1; AT3G43550.1; AT3G43550.
DR GeneID; 823449; -.
DR Gramene; AT3G43550.1; AT3G43550.1; AT3G43550.
DR KEGG; ath:AT3G43550; -.
DR Araport; AT3G43550; -.
DR TAIR; locus:2098209; AT3G43550.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; Q3EAQ9; -.
DR OMA; PKKYGRF; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q3EAQ9; -.
DR BioCyc; ARA:AT3G43550-MON; -.
DR PRO; PR:Q3EAQ9; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q3EAQ9; baseline.
DR Genevisible; Q3EAQ9; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR008265; Lipase_GDSL_AS.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
DR PROSITE; PS01098; LIPASE_GDSL_SER; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..288
FT /note="GDSL esterase/lipase At3g43550"
FT /id="PRO_0000367396"
FT ACT_SITE 37
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT CARBOHYD 25
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 288 AA; 32179 MW; 009A291186D7B0E6 CRC64;
MKLQIIWLAL VLIAVETYAV KQGKNVTIPA LIVFGDSIMD TGNNNNLPTL LKCNFPPYGK
DYPGGFATGR FSDGRVPSDL IAEKLGLVKT LPAYMNPYLK PHDLLKGVTF ASGGTGYDPL
TAKIMSVISV WDQLIYFKEY ISKIKRHFGE EKAKDILEHS FFLVVSSSND LAHTYLAQAH
RYDRTSYANF LADSAVHFVR ELHKLGARKI GVFSAVPVGC VPLQRTVFGG FFTRGCNQPL
NNMAKQFNAR LSPALDSLDK ELDGVIIYIN VYDTLFDMIQ HPKKYGRF
