GDL5_ARATH
ID GDL5_ARATH Reviewed; 345 AA.
AC Q9ZUE4; Q9LQC7;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=GDSL esterase/lipase At1g23500;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g23500;
DE Flags: Precursor;
GN OrderedLocusNames=At1g23500; ORFNames=F28C11.13, F5O8.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79588.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC005990; AAC98006.1; -; Genomic_DNA.
DR EMBL; AC007945; AAF79588.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE30395.1; -; Genomic_DNA.
DR PIR; F86368; F86368.
DR RefSeq; NP_173764.1; NM_102199.1.
DR AlphaFoldDB; Q9ZUE4; -.
DR SMR; Q9ZUE4; -.
DR PaxDb; Q9ZUE4; -.
DR PRIDE; Q9ZUE4; -.
DR ProteomicsDB; 221982; -.
DR EnsemblPlants; AT1G23500.1; AT1G23500.1; AT1G23500.
DR GeneID; 838958; -.
DR Gramene; AT1G23500.1; AT1G23500.1; AT1G23500.
DR KEGG; ath:AT1G23500; -.
DR Araport; AT1G23500; -.
DR TAIR; locus:2028868; AT1G23500.
DR eggNOG; ENOG502R6GS; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; Q9ZUE4; -.
DR OMA; CNFFPYG; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9ZUE4; -.
DR BioCyc; ARA:AT1G23500-MON; -.
DR PRO; PR:Q9ZUE4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9ZUE4; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR008265; Lipase_GDSL_AS.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
DR PROSITE; PS01098; LIPASE_GDSL_SER; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..345
FT /note="GDSL esterase/lipase At1g23500"
FT /id="PRO_0000367347"
FT ACT_SITE 42
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 320
FT /evidence="ECO:0000250"
FT ACT_SITE 323
FT /evidence="ECO:0000250"
FT CARBOHYD 103
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 345 AA; 37472 MW; 98368ABBB60A9C1E CRC64;
MNFSLLSTML MALSSVCLFF VGYAQQFSGS VAVSALFAFG DSILDTGNNN NLNTLSKCNF
FPYGRNFIGG KATGRFGNGR VFSDMIAEGL NVKKLLPAYR DPNLSKNDLP TGVCFASGGS
GLDERTARSQ GVIWVPDQVK DFKEYIMKLN GVVRDKRKVN AIISNAVYLI SAGNNDLAIT
YPTLMAQYTV STYTDLLVTW TDNLLKSLYA MGARKFAVLG TLPLGCLPGA RHTGGNFGNI
CLVPINQVAA IFNQKLSAKL NNLHTILPGA KFVYVDMYNP LLNLINNPRA SGFIDVADGC
CCMPTSPVPC PDASQYVFWD FAHPSEKSYM TIAPKIIEGI KKNLA
