GDL6_ARATH
ID GDL6_ARATH Reviewed; 389 AA.
AC Q9FXJ1; Q3ED52;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=GDSL esterase/lipase At1g28570;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At1g28570;
DE Flags: Precursor;
GN OrderedLocusNames=At1g28570; ORFNames=F1K23.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [4]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9FXJ1-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9FXJ1-2; Sequence=VSP_036686;
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC007508; AAG22837.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30994.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30995.1; -; Genomic_DNA.
DR RefSeq; NP_174179.3; NM_102625.4. [Q9FXJ1-1]
DR RefSeq; NP_973930.1; NM_202201.1. [Q9FXJ1-2]
DR AlphaFoldDB; Q9FXJ1; -.
DR SMR; Q9FXJ1; -.
DR PaxDb; Q9FXJ1; -.
DR PRIDE; Q9FXJ1; -.
DR ProteomicsDB; 221986; -. [Q9FXJ1-1]
DR EnsemblPlants; AT1G28570.1; AT1G28570.1; AT1G28570. [Q9FXJ1-1]
DR EnsemblPlants; AT1G28570.2; AT1G28570.2; AT1G28570. [Q9FXJ1-2]
DR GeneID; 839757; -.
DR Gramene; AT1G28570.1; AT1G28570.1; AT1G28570. [Q9FXJ1-1]
DR Gramene; AT1G28570.2; AT1G28570.2; AT1G28570. [Q9FXJ1-2]
DR KEGG; ath:AT1G28570; -.
DR Araport; AT1G28570; -.
DR TAIR; locus:2018673; AT1G28570.
DR eggNOG; ENOG502QSMM; Eukaryota.
DR InParanoid; Q9FXJ1; -.
DR OMA; NSESRFK; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9FXJ1; -.
DR BioCyc; ARA:AT1G28570-MON; -.
DR PRO; PR:Q9FXJ1; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FXJ1; baseline and differential.
DR Genevisible; Q9FXJ1; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Glycoprotein; Hydrolase; Lipid degradation;
KW Lipid metabolism; Reference proteome; Secreted; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..389
FT /note="GDSL esterase/lipase At1g28570"
FT /id="PRO_0000367348"
FT ACT_SITE 41
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 344
FT /evidence="ECO:0000250"
FT ACT_SITE 347
FT /evidence="ECO:0000250"
FT CARBOHYD 137
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 319
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VAR_SEQ 88..159
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000305"
FT /id="VSP_036686"
SQ SEQUENCE 389 AA; 43301 MW; 04A47AE1E132EE31 CRC64;
MATLFMKLVS FFLILSTFCL TTVNSEPQCH NFKSIISFGD SIADTGNLLA LSDPTNLPKV
AFLPYGETFF HHPTGRFSNG RLIIDFIAEF LGFPLVPPFY GSQNANFEKG VNFAVGGATA
LERSFLEERG IHFPYTNVSL AVQLSSFKES LPNLCVSPSD CRDMIENSLI LMGEIGGNDY
NYAFFVGKNI EEIKELVPLV IETISSAITE LIGMGGKTFL VPGEFPLGCS VAYLSLYQTS
NIEEYDPLTG CLKWLNKFSE YHDEQLQAEL NRLQKLYPHV NIIYADYYNT LLRLAQEPAK
FGFISRPLPA CCALGGPFNF TLGRKRGTQV PECCDDPSKY VSWDGVHMTE AAYRLMAEGI
LKGPYAIPPF DWSCLSSEIK NTQNSLMNN
