ID   GDL70_ARATH             Reviewed;         322 AA.
AC   Q9LZS8;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=GDSL esterase/lipase At5g03600;
DE            EC=3.1.1.-;
GN   OrderedLocusNames=At5g03600; ORFNames=F17C15.20;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   REVIEW.
RX   PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA   Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT   "GDSL family of serine esterases/lipases.";
RL   Prog. Lipid Res. 43:534-552(2004).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA   Ling H.;
RT   "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL   Pak. J. Biol. Sci. 11:763-767(2008).
CC   -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC       {ECO:0000305}.
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DR   EMBL; AL162506; CAB82925.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED90632.1; -; Genomic_DNA.
DR   PIR; T48387; T48387.
DR   RefSeq; NP_001318471.1; NM_001342720.1.
DR   AlphaFoldDB; Q9LZS8; -.
DR   SMR; Q9LZS8; -.
DR   PaxDb; Q9LZS8; -.
DR   PRIDE; Q9LZS8; -.
DR   ProteomicsDB; 247106; -.
DR   EnsemblPlants; AT5G03600.1; AT5G03600.1; AT5G03600.
DR   GeneID; 831781; -.
DR   Gramene; AT5G03600.1; AT5G03600.1; AT5G03600.
DR   KEGG; ath:AT5G03600; -.
DR   Araport; AT5G03600; -.
DR   TAIR; locus:2144548; AT5G03600.
DR   eggNOG; ENOG502QU3Y; Eukaryota.
DR   HOGENOM; CLU_015101_12_0_1; -.
DR   InParanoid; Q9LZS8; -.
DR   OMA; EAWALPY; -.
DR   PhylomeDB; Q9LZS8; -.
DR   PRO; PR:Q9LZS8; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LZS8; baseline and differential.
DR   Genevisible; Q9LZS8; AT.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd01837; SGNH_plant_lipase_like; 1.
DR   Gene3D; 3.40.50.1110; -; 1.
DR   InterPro; IPR001087; GDSL.
DR   InterPro; IPR036514; SGNH_hydro_sf.
DR   InterPro; IPR035669; SGNH_plant_lipase-like.
DR   Pfam; PF00657; Lipase_GDSL; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Lipid degradation; Lipid metabolism; Reference proteome.
FT   CHAIN           1..322
FT                   /note="GDSL esterase/lipase At5g03600"
FT                   /id="PRO_0000367410"
FT   ACT_SITE        21
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        295
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        298
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   322 AA;  35723 MW;  813A0210BC3D277E CRC64;
     MGSNQLLRPR KVPKLFVFGD SYADTGNTKR DTEAWAIPYG ITFPGKPSGR YCDGLIATDF
     LEKVLGAESP YLYRTHGRDK GLKRGMNFAF GGSKMLDSSP NSPFPNITAQ VNFLVDLVLA
     GRVYGDITPS DVSLISYAGG DYIYYIDQNR PAAGLKALVE KVVDNLRVNM IVLGGLLFKK
     IAVTSLQPIG CLPSYTSASS FKSCNESQSA LVELHNKLLK KVVAKLNEQS RVMKKEQHFF
     IIDIHNAFMT VMKNKGSKRF KNPMKSCCEG YCGRSSDGGK LYTLCDDPKS FFFWDAVHPT
     QEGWRSIYSV LGNPLTDFLT KP