GDL77_ARATH
ID GDL77_ARATH Reviewed; 362 AA.
AC Q5PNZ0;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=GDSL esterase/lipase At5g18430;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At5g18430;
DE Flags: Precursor;
GN OrderedLocusNames=At5g18430; ORFNames=F20L16.150;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AC051626; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED92562.1; -; Genomic_DNA.
DR EMBL; BT020307; AAV85662.1; -; mRNA.
DR EMBL; BT020574; AAW78593.1; -; mRNA.
DR RefSeq; NP_197344.2; NM_121848.4.
DR AlphaFoldDB; Q5PNZ0; -.
DR SMR; Q5PNZ0; -.
DR STRING; 3702.AT5G18430.1; -.
DR PaxDb; Q5PNZ0; -.
DR PRIDE; Q5PNZ0; -.
DR ProteomicsDB; 247108; -.
DR EnsemblPlants; AT5G18430.1; AT5G18430.1; AT5G18430.
DR GeneID; 831961; -.
DR Gramene; AT5G18430.1; AT5G18430.1; AT5G18430.
DR KEGG; ath:AT5G18430; -.
DR Araport; AT5G18430; -.
DR TAIR; locus:2146223; AT5G18430.
DR eggNOG; ENOG502QQP0; Eukaryota.
DR HOGENOM; CLU_015101_0_0_1; -.
DR InParanoid; Q5PNZ0; -.
DR OMA; NGRCSAE; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q5PNZ0; -.
DR PRO; PR:Q5PNZ0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q5PNZ0; baseline and differential.
DR Genevisible; Q5PNZ0; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..362
FT /note="GDSL esterase/lipase At5g18430"
FT /id="PRO_0000367417"
FT ACT_SITE 35
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 327
FT /evidence="ECO:0000250"
FT ACT_SITE 330
FT /evidence="ECO:0000250"
FT CARBOHYD 117
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 355
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 362 AA; 40123 MW; 2E2B185A113A4F96 CRC64;
MTISTVIAFM SMFLVFVMSG PIVVEGRAFF VFGDSLVDSG NNNYLVTTAR ADSPPYGIDF
PTRRPTGRFS NGLNIPDLIS EAIGNEEPPL PYLSPELRGR SLLNGANFAS AGIGILNDTG
FQFINIIRMY QQLDYFQQYQ QRVSRLIGKP QTQRLVSQAL VLITVGGNDF VNNYFLFPYS
ARSRQFTLPD YVRLLISEYK KILLRLNSLG VGRVLVTGAG PLGCAPAELA RSGTSNGRCS
AELQRAASLY DPQLLQMINE LNKKIGRNVF IAANTNQMQE DFLSTPRRYG FVTSKVACCG
QGPYNGMGLC TVLSNLCPNR ELYVFWDAFH PTEKANRMIV RHILTGTTKY MNPMNLSSAL
AL
