GDL80_ARATH
ID GDL80_ARATH Reviewed; 356 AA.
AC Q9FHQ1; Q8LF30;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=GDSL esterase/lipase At5g37690;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At5g37690;
DE Flags: Precursor;
GN OrderedLocusNames=At5g37690; ORFNames=K12B20.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10470850; DOI=10.1093/dnares/6.3.183;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Kotani H.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence
RT features of the regions of 1,011,550 bp covered by seventeen P1 and TAC
RT clones.";
RL DNA Res. 6:183-195(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AB018107; BAB08315.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94220.1; -; Genomic_DNA.
DR EMBL; AY085078; AAM61634.1; -; mRNA.
DR RefSeq; NP_198585.2; NM_123128.3.
DR AlphaFoldDB; Q9FHQ1; -.
DR SMR; Q9FHQ1; -.
DR STRING; 3702.AT5G37690.1; -.
DR PaxDb; Q9FHQ1; -.
DR PRIDE; Q9FHQ1; -.
DR ProteomicsDB; 221990; -.
DR DNASU; 833748; -.
DR EnsemblPlants; AT5G37690.1; AT5G37690.1; AT5G37690.
DR GeneID; 833748; -.
DR Gramene; AT5G37690.1; AT5G37690.1; AT5G37690.
DR KEGG; ath:AT5G37690; -.
DR Araport; AT5G37690; -.
DR TAIR; locus:2151744; AT5G37690.
DR eggNOG; ENOG502QW3W; Eukaryota.
DR HOGENOM; CLU_015101_0_0_1; -.
DR InParanoid; Q9FHQ1; -.
DR OMA; YLTYCLA; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9FHQ1; -.
DR BioCyc; ARA:AT5G37690-MON; -.
DR PRO; PR:Q9FHQ1; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FHQ1; baseline and differential.
DR Genevisible; Q9FHQ1; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..356
FT /note="GDSL esterase/lipase At5g37690"
FT /id="PRO_0000367420"
FT ACT_SITE 34
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 322
FT /evidence="ECO:0000250"
FT ACT_SITE 325
FT /evidence="ECO:0000250"
FT CARBOHYD 116
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 291
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 14
FT /note="T -> A (in Ref. 3; AAM61634)"
FT /evidence="ECO:0000305"
FT CONFLICT 155
FT /note="V -> I (in Ref. 3; AAM61634)"
FT /evidence="ECO:0000305"
FT CONFLICT 356
FT /note="Missing (in Ref. 3; AAM61634)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 356 AA; 39211 MW; EC3878F13D84A7D5 CRC64;
MMILRLALAI VISTYATAQP ASTSSLVTYI FGDSLTEVGN NNFLQYSLAR ADFPYYGVDF
SGGKATGRFT NGRTIGDIIS TKLGILSPPP YLSLSQNDDA FLSGINYASG GAGILNETGI
YFIQRLTFND QINCFKKTKE VIRAKIGDGA ANKHVNDAMY FIGLGSNDYV NNFLQPFMAD
GQQYTHDEFV ELLTSTLHNQ LTTIYKLGAR KVIFHGLGPL GCIPSQRVKS KTRMCLNRVN
EWVLEFNSRT KKLLIDLNKR LPGAKFSFAD TYPAVLDLIN NPTHYGFKIA NTSCCNVDTS
VGGLCLPNSK MCKNRQDFVF WDAFHPSDSA NQILADHLFS SLLSSSSPSP APKPRQ
