GDL82_ARATH
ID GDL82_ARATH Reviewed; 362 AA.
AC Q9FK75; Q8LDT8;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=GDSL esterase/lipase At5g45670;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At5g45670;
DE Flags: Precursor;
GN OrderedLocusNames=At5g45670; ORFNames=MRA19.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [6]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AB012245; BAB09209.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95282.1; -; Genomic_DNA.
DR EMBL; AF446366; AAL48238.1; -; mRNA.
DR EMBL; AY097424; AAM19940.1; -; mRNA.
DR EMBL; AY085805; AAM63021.1; -; mRNA.
DR RefSeq; NP_199379.1; NM_123934.4.
DR AlphaFoldDB; Q9FK75; -.
DR SMR; Q9FK75; -.
DR STRING; 3702.AT5G45670.1; -.
DR SwissPalm; Q9FK75; -.
DR PaxDb; Q9FK75; -.
DR PRIDE; Q9FK75; -.
DR ProteomicsDB; 221992; -.
DR EnsemblPlants; AT5G45670.1; AT5G45670.1; AT5G45670.
DR GeneID; 834606; -.
DR Gramene; AT5G45670.1; AT5G45670.1; AT5G45670.
DR KEGG; ath:AT5G45670; -.
DR Araport; AT5G45670; -.
DR TAIR; locus:2171948; AT5G45670.
DR eggNOG; KOG0017; Eukaryota.
DR HOGENOM; CLU_015101_0_0_1; -.
DR InParanoid; Q9FK75; -.
DR OMA; SNYLSKC; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9FK75; -.
DR BioCyc; ARA:AT5G45670-MON; -.
DR PRO; PR:Q9FK75; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FK75; baseline and differential.
DR Genevisible; Q9FK75; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Hydrolase; Lipid degradation; Lipid metabolism; Reference proteome;
KW Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..362
FT /note="GDSL esterase/lipase At5g45670"
FT /id="PRO_0000367422"
FT ACT_SITE 36
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 326
FT /evidence="ECO:0000250"
FT ACT_SITE 329
FT /evidence="ECO:0000250"
FT CONFLICT 350
FT /note="D -> N (in Ref. 4; AAM63021)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 362 AA; 39576 MW; D305B2CE3042A7CC CRC64;
MARMSLMIMM IMVAVTMINI AKSDPIAPCY FIFGDSLVDN GNNNQLQSLA RANYFPYGID
FAAGPTGRFS NGLTTVDVIA QLLGFEDYIT PYASARGQDI LRGVNYASAA AGIRDETGRQ
LGGRIAFAGQ VANHVNTVSQ VVNILGDQNE ASNYLSKCIY SIGLGSNDYL NNYFMPTFYS
TGNQFSPESY ADDLVARYTE QLRVLYTNGA RKFALIGVGA IGCSPNELAQ NSRDGRTCDE
RINSANRIFN SKLISIVDAF NQNTPDAKFT YINAYGIFQD IITNPARYGF RVTNAGCCGV
GRNNGQITCL PGQAPCLNRN EYVFWDAFHP GEAANIVIGR RSFKREAASD AHPYDIQQLA
SL
