GDL85_ARATH
ID GDL85_ARATH Reviewed; 357 AA.
AC Q9FJ41; Q56ZU9;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=GDSL esterase/lipase At5g45950;
DE EC=3.1.1.-;
DE AltName: Full=Extracellular lipase At5g45950;
DE Flags: Precursor;
GN OrderedLocusNames=At5g45950; ORFNames=K15I22.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 245-357.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP REVIEW.
RX PubMed=15522763; DOI=10.1016/j.plipres.2004.09.002;
RA Akoh C.C., Lee G.-C., Liaw Y.-C., Huang T.-H., Shaw J.-F.;
RT "GDSL family of serine esterases/lipases.";
RL Prog. Lipid Res. 43:534-552(2004).
RN [5]
RP GENE FAMILY.
RX PubMed=18819574; DOI=10.3923/pjbs.2008.763.767;
RA Ling H.;
RT "Sequence analysis of GDSL lipase gene family in Arabidopsis thaliana.";
RL Pak. J. Biol. Sci. 11:763-767(2008).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'GDSL' lipolytic enzyme family.
CC {ECO:0000305}.
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DR EMBL; AB016870; BAB09323.1; -; Genomic_DNA.
DR EMBL; CP002688; AED95319.1; -; Genomic_DNA.
DR EMBL; AK220862; BAD94226.1; -; mRNA.
DR RefSeq; NP_199407.1; NM_123963.4.
DR AlphaFoldDB; Q9FJ41; -.
DR SMR; Q9FJ41; -.
DR STRING; 3702.AT5G45950.1; -.
DR PaxDb; Q9FJ41; -.
DR PRIDE; Q9FJ41; -.
DR ProteomicsDB; 247112; -.
DR EnsemblPlants; AT5G45950.1; AT5G45950.1; AT5G45950.
DR GeneID; 834635; -.
DR Gramene; AT5G45950.1; AT5G45950.1; AT5G45950.
DR KEGG; ath:AT5G45950; -.
DR Araport; AT5G45950; -.
DR TAIR; locus:2152425; AT5G45950.
DR eggNOG; ENOG502R619; Eukaryota.
DR HOGENOM; CLU_015101_0_1_1; -.
DR InParanoid; Q9FJ41; -.
DR OMA; RHYEIHL; -.
DR OrthoDB; 704138at2759; -.
DR PhylomeDB; Q9FJ41; -.
DR BioCyc; ARA:AT5G45950-MON; -.
DR PRO; PR:Q9FJ41; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FJ41; baseline and differential.
DR Genevisible; Q9FJ41; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd01837; SGNH_plant_lipase_like; 1.
DR Gene3D; 3.40.50.1110; -; 1.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR InterPro; IPR035669; SGNH_plant_lipase-like.
DR Pfam; PF00657; Lipase_GDSL; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Hydrolase; Lipid degradation; Lipid metabolism;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..357
FT /note="GDSL esterase/lipase At5g45950"
FT /id="PRO_0000367425"
FT ACT_SITE 47
FT /note="Nucleophile"
FT /evidence="ECO:0000250"
FT ACT_SITE 331
FT /evidence="ECO:0000250"
FT ACT_SITE 334
FT /evidence="ECO:0000250"
FT CARBOHYD 37
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 132
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 357 AA; 39854 MW; 84C8826E392DD8DB CRC64;
MLLVAFVTLL VAVALQPLPS VLSLDVHLLR QLAAKHNVTS ILVFGDSSVD PGNNNFIKTE
MKGNFPPYGE NFINHKPTGR LCDGLLAPDY IAEAMGYPPI PAFLDPSLTQ ADLTRGASFA
SAGSGYDDLT ANISNVWSFT TQANYFLHYK IHLTKLVGPL ESAKMINNAI FLMSMGSNDF
LQNYLVDFTR QKQFTVEQYI EFLSHRMLYD AKMLHRLGAK RLVVVGVPPM GCMPLIKYLR
GQKTCVDQLN QIAFSFNAKI IKNLELLQSK IGLKTIYVDA YSTIQEAIKN PRKFGFVEAS
LGCCGTGTYE YGETCKDMQV CKDPTKYVFW DAVHPTQRMY QIIVKKAIAS ISEEFLV
