ID   GDNC_BACLD              Reviewed;         109 AA.
AC   Q65KV1;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Probable guanidinium efflux system subunit GdnC {ECO:0000250|UniProtKB:P49856};
GN   Name=gdnC {ECO:0000250|UniProtKB:P49856}; Synonyms=ykkC;
GN   OrderedLocusNames=BLi01409, BL03755;
OS   Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 /
OS   NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=279010;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375
RC   / NCTC 10341 / NRRL NRS-1264 / Gibson 46;
RX   PubMed=15383718; DOI=10.1159/000079829;
RA   Veith B., Herzberg C., Steckel S., Feesche J., Maurer K.H., Ehrenreich P.,
RA   Baeumer S., Henne A., Liesegang H., Merkl R., Ehrenreich A., Gottschalk G.;
RT   "The complete genome sequence of Bacillus licheniformis DSM13, an organism
RT   with great industrial potential.";
RL   J. Mol. Microbiol. Biotechnol. 7:204-211(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375
RC   / NCTC 10341 / NRRL NRS-1264 / Gibson 46;
RX   PubMed=15461803; DOI=10.1186/gb-2004-5-10-r77;
RA   Rey M.W., Ramaiya P., Nelson B.A., Brody-Karpin S.D., Zaretsky E.J.,
RA   Tang M., Lopez de Leon A., Xiang H., Gusti V., Clausen I.G., Olsen P.B.,
RA   Rasmussen M.D., Andersen J.T., Joergensen P.L., Larsen T.S., Sorokin A.,
RA   Bolotin A., Lapidus A., Galleron N., Ehrlich S.D., Berka R.M.;
RT   "Complete genome sequence of the industrial bacterium Bacillus
RT   licheniformis and comparisons with closely related Bacillus species.";
RL   Genome Biol. 5:R77.1-R77.12(2004).
CC   -!- FUNCTION: Probably involved in guanidinium transport.
CC       {ECO:0000250|UniProtKB:P49856}.
CC   -!- SUBUNIT: The efflux pump is composed of GdnC and GdnD.
CC       {ECO:0000250|UniProtKB:P49856}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
CC       YkkC/YkkD subfamily. {ECO:0000305}.
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DR   EMBL; AE017333; AAU40313.1; -; Genomic_DNA.
DR   EMBL; CP000002; AAU22960.1; -; Genomic_DNA.
DR   RefSeq; WP_003180979.1; NC_006322.1.
DR   AlphaFoldDB; Q65KV1; -.
DR   SMR; Q65KV1; -.
DR   STRING; 279010.BL03755; -.
DR   DNASU; 3030456; -.
DR   EnsemblBacteria; AAU22960; AAU22960; BL03755.
DR   GeneID; 66216458; -.
DR   KEGG; bld:BLi01409; -.
DR   KEGG; bli:BL03755; -.
DR   eggNOG; COG2076; Bacteria.
DR   HOGENOM; CLU_133067_1_0_9; -.
DR   OMA; EVFWVIG; -.
DR   OrthoDB; 1990300at2; -.
DR   BioCyc; BLIC279010:BLI_RS07000-MON; -.
DR   Proteomes; UP000000606; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   InterPro; IPR045324; Small_multidrug_res.
DR   PANTHER; PTHR30561; PTHR30561; 1.
DR   Pfam; PF00893; Multi_Drug_Res; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Ion transport; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..109
FT                   /note="Probable guanidinium efflux system subunit GdnC"
FT                   /id="PRO_0000108110"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   109 AA;  11426 MW;  5325EDBD7ED5E838 CRC64;
     MRWGSVILAA LFEIGWVMGL KHADSALEWI CTAAAVVMSF YILVKAGEKL PVGTVYAVFT
     GLGTAGTVVC EIALFNEPAN IAKLALIGVL LCGVIGLKLV TNEEKGEAS