GDPD2_ARATH
ID GDPD2_ARATH Reviewed; 374 AA.
AC Q9FLM1;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=Glycerophosphodiester phosphodiesterase GDPD2 {ECO:0000305};
DE EC=3.1.4.46 {ECO:0000250|UniProtKB:Q9SGA2};
DE AltName: Full=Glycerophosphodiester phosphodiesterase 2 {ECO:0000303|PubMed:21323773};
DE Short=AtGDPD2 {ECO:0000303|PubMed:21323773};
GN Name=GDPD2 {ECO:0000303|PubMed:21323773};
GN OrderedLocusNames=At5g41080 {ECO:0000312|Araport:AT5G41080};
GN ORFNames=MEE6.15 {ECO:0000312|EMBL:BAB09710.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Wu S.Y., De Los Reyes C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TISSUE SPECIFICITY, INDUCTION, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=21323773; DOI=10.1111/j.1365-313x.2011.04538.x;
RA Cheng Y., Zhou W., El Sheery N.I., Peters C., Li M., Wang X., Huang J.;
RT "Characterization of the Arabidopsis glycerophosphodiester
RT phosphodiesterase (GDPD) family reveals a role of the plastid-localized
RT AtGDPD1 in maintaining cellular phosphate homeostasis under phosphate
RT starvation.";
RL Plant J. 66:781-795(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-
CC glycerol 3-phosphate; Xref=Rhea:RHEA:12969, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30879, ChEBI:CHEBI:57597,
CC ChEBI:CHEBI:83408; EC=3.1.4.46;
CC Evidence={ECO:0000250|UniProtKB:Q9SGA2};
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9FLM1-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Expressed in roots, shoots, flowers and siliques.
CC {ECO:0000269|PubMed:21323773}.
CC -!- INDUCTION: By phosphate starvation. {ECO:0000269|PubMed:21323773}.
CC -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC family. {ECO:0000305}.
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DR EMBL; AB010072; BAB09710.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94635.1; -; Genomic_DNA.
DR EMBL; AK117378; BAC42047.1; -; mRNA.
DR EMBL; BT030021; ABN04759.1; -; mRNA.
DR RefSeq; NP_198924.1; NM_123473.4. [Q9FLM1-1]
DR AlphaFoldDB; Q9FLM1; -.
DR SMR; Q9FLM1; -.
DR STRING; 3702.AT5G41080.1; -.
DR PaxDb; Q9FLM1; -.
DR ProteomicsDB; 222000; -. [Q9FLM1-1]
DR DNASU; 834110; -.
DR EnsemblPlants; AT5G41080.1; AT5G41080.1; AT5G41080. [Q9FLM1-1]
DR GeneID; 834110; -.
DR Gramene; AT5G41080.1; AT5G41080.1; AT5G41080. [Q9FLM1-1]
DR KEGG; ath:AT5G41080; -.
DR Araport; AT5G41080; -.
DR TAIR; locus:2163031; AT5G41080.
DR eggNOG; KOG2421; Eukaryota.
DR InParanoid; Q9FLM1; -.
DR OMA; HANERPI; -.
DR OrthoDB; 687958at2759; -.
DR PhylomeDB; Q9FLM1; -.
DR PRO; PR:Q9FLM1; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FLM1; baseline and differential.
DR Genevisible; Q9FLM1; AT.
DR GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:UniProtKB-EC.
DR GO; GO:0071456; P:cellular response to hypoxia; HEP:TAIR.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0046475; P:glycerophospholipid catabolic process; IBA:GO_Central.
DR Gene3D; 3.20.20.190; -; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR Pfam; PF03009; GDPD; 1.
DR SUPFAM; SSF51695; SSF51695; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycerol metabolism; Hydrolase; Reference proteome.
FT CHAIN 1..374
FT /note="Glycerophosphodiester phosphodiesterase GDPD2"
FT /id="PRO_0000430608"
FT DOMAIN 38..326
FT /note="GP-PDE"
FT /evidence="ECO:0000255"
FT REGION 330..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 42016 MW; 733143BAD06F03ED CRC64;
MALRTVLVSD VPSLPDSVYG LSEGLELSKP TSFRLPGFSV IGHRGIGMNV LQSSDRRARG
VKENSILSFN SAAKYPIDFI EFDVQVTKDD CPVIFHDDFI YSEENGIVNE SRVTDLSLSE
FLLYGPQKET EKIGKTLMRK SKEGKVLKWD VDLDDSLCTL QEAFEQVEQT LGFNIELKFD
DQTVYEREFL VHILRSVLQV VSNYAKDRPV IFSSFQPDAA KLVRELQSTY PVFFLTDAGN
EIHNDERRNS LEEAIQVCLE GGLQGIVSEV KGVFRNPAAI SKIKESNLSL LTYGKLNNVG
EAVYMQYVMG IDGVIVDFVE EIIESTTRMM IRPPPSSSPL PSPSKDDDVA ITRPEFSQKE
ISFLLKLLSQ LIQH
