GDPD4_ARATH
ID GDPD4_ARATH Reviewed; 328 AA.
AC F4I8H8; Q9FVW0;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Glycerophosphodiester phosphodiesterase GDPD4 {ECO:0000305};
DE EC=3.1.4.46 {ECO:0000250|UniProtKB:Q9SGA2};
DE AltName: Full=Glycerophosphodiester phosphodiesterase 4 {ECO:0000303|PubMed:21323773};
DE Short=ATGDPD4 {ECO:0000303|PubMed:21323773};
GN Name=GDPD4 {ECO:0000303|PubMed:21323773};
GN OrderedLocusNames=At1g71340 {ECO:0000312|Araport:AT1G71340};
GN ORFNames=F3I17.1 {ECO:0000312|EMBL:AAG51889.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AEE35191.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=21323773; DOI=10.1111/j.1365-313x.2011.04538.x;
RA Cheng Y., Zhou W., El Sheery N.I., Peters C., Li M., Wang X., Huang J.;
RT "Characterization of the Arabidopsis glycerophosphodiester
RT phosphodiesterase (GDPD) family reveals a role of the plastid-localized
RT AtGDPD1 in maintaining cellular phosphate homeostasis under phosphate
RT starvation.";
RL Plant J. 66:781-795(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-
CC glycerol 3-phosphate; Xref=Rhea:RHEA:12969, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30879, ChEBI:CHEBI:57597,
CC ChEBI:CHEBI:83408; EC=3.1.4.46;
CC Evidence={ECO:0000250|UniProtKB:Q9SGA2};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC protein {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Expressed in rosette and cauline leaves.
CC {ECO:0000269|PubMed:21323773}.
CC -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG51889.1; Type=Erroneous gene model prediction;
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DR EMBL; AC016162; AAG51889.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE35191.1; -; Genomic_DNA.
DR PIR; C96738; C96738.
DR RefSeq; NP_177290.3; NM_105803.5.
DR AlphaFoldDB; F4I8H8; -.
DR SMR; F4I8H8; -.
DR STRING; 3702.AT1G71340.1; -.
DR PaxDb; F4I8H8; -.
DR PRIDE; F4I8H8; -.
DR ProteomicsDB; 247117; -.
DR EnsemblPlants; AT1G71340.1; AT1G71340.1; AT1G71340.
DR GeneID; 843475; -.
DR Gramene; AT1G71340.1; AT1G71340.1; AT1G71340.
DR KEGG; ath:AT1G71340; -.
DR Araport; AT1G71340; -.
DR TAIR; locus:2032323; AT1G71340.
DR eggNOG; KOG2258; Eukaryota.
DR HOGENOM; CLU_055532_0_0_1; -.
DR InParanoid; F4I8H8; -.
DR OMA; QCKNCIV; -.
DR OrthoDB; 1218115at2759; -.
DR PRO; PR:F4I8H8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4I8H8; baseline and differential.
DR Genevisible; F4I8H8; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:UniProtKB-EC.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.190; -; 1.
DR InterPro; IPR044236; GDPD4.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR PANTHER; PTHR47449; PTHR47449; 1.
DR Pfam; PF03009; GDPD; 1.
DR SUPFAM; SSF51695; SSF51695; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 2: Evidence at transcript level;
KW Glycerol metabolism; Hydrolase; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..328
FT /note="Glycerophosphodiester phosphodiesterase GDPD4"
FT /id="PRO_0000430610"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 73..312
FT /note="GP-PDE"
FT /evidence="ECO:0000255"
SQ SEQUENCE 328 AA; 37374 MW; AFA4A81DC59AC79F CRC64;
MAIFEWRHRR RPFDGGGTRR RRFFSPLYSR NFKRTILFAV IFLAIFPPLY FHFKLRRIRQ
IVAQKCDWLH HPPLVCAHGG DSTLAFPNTM DAYSFAIRSR VDCIEVDVSR SSDGVLFALH
NRDLQRIARN SSVQVGDLSM KQIKELDVSE IVKGTLGSSR IPTLEEALAL ISNSVRKVIL
DAKVGPPMYE KGLAQDILSI IERAQCNNCI VWAKSDTLAR DIIRRAPDTM VGYIVMVDPL
TGARNSLLRM KGARVVGVYH PLIDEELVRV VRRRNKEVYA WTVDDADPMK RMLHLGVDAV
VTSDPSMFQG LMEDLRTECL EEGFSIRT
