GDPD5_ARATH
ID GDPD5_ARATH Reviewed; 392 AA.
AC Q9C907;
DT 29-OCT-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Glycerophosphodiester phosphodiesterase GDPD5 {ECO:0000305};
DE EC=3.1.4.46 {ECO:0000250|UniProtKB:Q9SGA2};
DE AltName: Full=Glycerophosphodiester phosphodiesterase 5 {ECO:0000303|PubMed:21323773};
DE Short=ATGDPD5 {ECO:0000303|PubMed:21323773};
DE Flags: Precursor;
GN Name=GDPD5 {ECO:0000303|PubMed:21323773};
GN OrderedLocusNames=At1g74210 {ECO:0000312|Araport:AT1G74210};
GN ORFNames=F1O17.12 {ECO:0000312|EMBL:AAG52406.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP SUBCELLULAR LOCATION.
RX PubMed=14750903; DOI=10.1042/bj20031489;
RA Van Der Rest B., Rolland N., Boisson A.M., Ferro M., Bligny R., Douce R.;
RT "Identification and characterization of plant glycerophosphodiester
RT phosphodiesterase.";
RL Biochem. J. 379:601-607(2004).
RN [6]
RP TISSUE SPECIFICITY, INDUCTION, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=21323773; DOI=10.1111/j.1365-313x.2011.04538.x;
RA Cheng Y., Zhou W., El Sheery N.I., Peters C., Li M., Wang X., Huang J.;
RT "Characterization of the Arabidopsis glycerophosphodiester
RT phosphodiesterase (GDPD) family reveals a role of the plastid-localized
RT AtGDPD1 in maintaining cellular phosphate homeostasis under phosphate
RT starvation.";
RL Plant J. 66:781-795(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-
CC glycerol 3-phosphate; Xref=Rhea:RHEA:12969, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30879, ChEBI:CHEBI:57597,
CC ChEBI:CHEBI:83408; EC=3.1.4.46;
CC Evidence={ECO:0000250|UniProtKB:Q9SGA2};
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC {ECO:0000303|PubMed:14750903}. Vacuole {ECO:0000303|PubMed:14750903}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, rosette and cauline leaves,
CC stems, flowers and siliques. {ECO:0000269|PubMed:21323773}.
CC -!- INDUCTION: By phosphate starvation. {ECO:0000269|PubMed:21323773}.
CC -!- SIMILARITY: Belongs to the glycerophosphoryl diester phosphodiesterase
CC family. {ECO:0000305}.
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DR EMBL; AC020579; AAG52406.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35566.1; -; Genomic_DNA.
DR EMBL; AY064037; AAL36393.1; -; mRNA.
DR EMBL; AY142654; AAN13192.1; -; mRNA.
DR EMBL; AY086343; AAM64411.1; -; mRNA.
DR PIR; D96770; D96770.
DR RefSeq; NP_177561.1; NM_106081.3.
DR AlphaFoldDB; Q9C907; -.
DR SMR; Q9C907; -.
DR STRING; 3702.AT1G74210.1; -.
DR PaxDb; Q9C907; -.
DR PRIDE; Q9C907; -.
DR ProteomicsDB; 247118; -.
DR EnsemblPlants; AT1G74210.1; AT1G74210.1; AT1G74210.
DR GeneID; 843761; -.
DR Gramene; AT1G74210.1; AT1G74210.1; AT1G74210.
DR KEGG; ath:AT1G74210; -.
DR Araport; AT1G74210; -.
DR TAIR; locus:2019642; AT1G74210.
DR eggNOG; KOG2258; Eukaryota.
DR HOGENOM; CLU_030226_4_1_1; -.
DR InParanoid; Q9C907; -.
DR OMA; CRHENDI; -.
DR OrthoDB; 1143305at2759; -.
DR PhylomeDB; Q9C907; -.
DR BioCyc; ARA:AT1G74210-MON; -.
DR PRO; PR:Q9C907; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C907; baseline and differential.
DR Genevisible; Q9C907; AT.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IBA:GO_Central.
DR GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.190; -; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR Pfam; PF03009; GDPD; 1.
DR SUPFAM; SSF51695; SSF51695; 1.
DR PROSITE; PS51704; GP_PDE; 1.
PE 2: Evidence at transcript level;
KW Cell wall; Glycerol metabolism; Glycoprotein; Hydrolase;
KW Reference proteome; Secreted; Signal; Vacuole.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..392
FT /note="Glycerophosphodiester phosphodiesterase GDPD5"
FT /evidence="ECO:0000255"
FT /id="PRO_0000430612"
FT DOMAIN 44..362
FT /note="GP-PDE"
FT /evidence="ECO:0000255"
FT CARBOHYD 120
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 239
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 260
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 329
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 392 AA; 45021 MW; 4FAD45CE01756C3B CRC64;
MILTRCLPLI WLSLLTVCAA GRTLHPLPVK GPKTVKLQLQ TSRPYNIAHR GSNGEIPEET
TAAYLKAIEE GTDFIETDIL SSKDGVLICF HDCILDETTN VASHKEFADR KRTYDVQGFN
ITGFFTFDFT LKELKQLRIK QRYAFRDQQY NGMYPIITFE EFLTIARDAP RVVGIYPEIK
NPVLMNQHVK WPGGKKFEDK VVETLKKYGY GGSYLSKKWL KKPLFIQSFA PTSLVYISNL
TDSPKVLLID DVTMPTQDTN QTYAEITSDA YFEYIKQYVV GIGPWKDTIV PVNNNYVLAP
TDLVKRAHAH NLQVHPYTYR NEHEFLHYNF SQDPYKEYDY WINEIGVDGL FTDFTGSLHN
FQEWTSPLPD TSKSPRQLLS QIASLVLPYA KA
