ID   GDT7_DICDI              Reviewed;         801 AA.
AC   Q54DE3;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Growth-differentiation transition protein 7;
DE   Flags: Precursor;
GN   Name=gdt7; ORFNames=DDB_G0292314;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   IDENTIFICATION, AND NOMENCLATURE.
RX   PubMed=15236669; DOI=10.1186/1471-213x-4-8;
RA   Chibalina M.V., Anjard C., Insall R.H.;
RT   "Gdt2 regulates the transition of Dictyostelium cells from growth to
RT   differentiation.";
RL   BMC Dev. Biol. 4:8-8(2004).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GDT family. {ECO:0000305}.
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DR   EMBL; AAFI02000189; EAL61281.1; -; Genomic_DNA.
DR   RefSeq; XP_629698.1; XM_629696.1.
DR   AlphaFoldDB; Q54DE3; -.
DR   STRING; 44689.DDB0220635; -.
DR   PaxDb; Q54DE3; -.
DR   EnsemblProtists; EAL61281; EAL61281; DDB_G0292314.
DR   GeneID; 8628613; -.
DR   KEGG; ddi:DDB_G0292314; -.
DR   dictyBase; DDB_G0292314; gdt7.
DR   HOGENOM; CLU_351415_0_0_1; -.
DR   InParanoid; Q54DE3; -.
DR   PhylomeDB; Q54DE3; -.
DR   PRO; PR:Q54DE3; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050793; P:regulation of developmental process; IBA:GO_Central.
DR   InterPro; IPR026237; STKINASEGDT.
DR   PRINTS; PR02079; STKINASEGDT.
PE   3: Inferred from homology;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..801
FT                   /note="Growth-differentiation transition protein 7"
FT                   /id="PRO_0000323584"
SQ   SEQUENCE   801 AA;  89743 MW;  1CE6F9B946C881CF CRC64;
     MIKTILIKLI LLVIFCYHFL FAEEDVISTP PGYYDLIRHK RDPPITEYQS SQDTDLYYPD
     VCRNALRPLD YPWINEFAPI FFPGFNMGGF NSIFIPKNRS MIFRTPFQDS LVTLHVVCIE
     GTFIVEGNRF LFANTIIVLP GGRFESTTGI EFYDENDSGV SFYPDLPKDP SGFFPGILVL
     GGSISVVGKE PIVYRASRIN DSSIEISPPV PEIIISPNPW DRVYKLVKIF TELYPLGFYC
     RYNTDEVGKI LSLSSYLLYP FPPVSENDKI IRVLVETDRQ QTVIPTNIYK REYATKGSIY
     ITGGSNAYFK NIFFKNLGFT KNEPYNDTKL IFSPNDTNVV TDIIMGTNQK FRSSLYIESS
     KNVTIEGCAF VENDLTRSPL VFFDSNVKIS NSLISSKSGS NIIALHGTDS IQSSNNSYLL
     EKIDLASWDV ERNNNIDCGN QGNGIFSISP NINSNGDYFS GQQTAFNYYF IPNNSVNSNQ
     DNSSLNSRPI EIIIKDSMFN PTASNGSLNK YFLNINTDGN KTISTYFTVR DLKTSHAINM
     NLNNSAIAFY NLKGGEGFKM EGNVERLDII GSIINSNGSI KNISTSTTNI IDSYIYSSSS
     DIQPFNNQIY GSLITPYYYS DSNTLDKFEI KSILPNAPIQ IVSGSLFNVS VQIQTLSSSV
     SIDNISCIFT SSVINTTVVQ VNSNYSCILP LNITNEEGPL NLRVTLVNNT SPSSVSSDNY
     LYIIDFPEIT VFNTYEFYSG WLMDNSNSSQ QISFGGNSFK NGCNKVDSNC TISQNSKYST
     VFSQLSITLP SNFKTKTHWM K