ID   GEI13_CAEEL             Reviewed;         691 AA.
AC   P34478;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 2.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Gex-3-interacting protein 13;
GN   Name=gei-13; ORFNames=F58A4.11;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=7906398; DOI=10.1038/368032a0;
RA   Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA   Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA   Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA   Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA   Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA   Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA   Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA   Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA   Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA   Wilkinson-Sproat J., Wohldman P.;
RT   "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT   elegans.";
RL   Nature 368:32-38(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [3]
RP   INTERACTION WITH GEX-3, AND DISRUPTION PHENOTYPE.
RX   PubMed=11922622; DOI=10.1006/bbrc.2002.6717;
RA   Tsuboi D., Qadota H., Kasuya K., Amano M., Kaibuchi K.;
RT   "Isolation of the interacting molecules with GEX-3 by a novel functional
RT   screening.";
RL   Biochem. Biophys. Res. Commun. 292:697-701(2002).
CC   -!- SUBUNIT: Interacts with gex-3. {ECO:0000269|PubMed:11922622}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC       {ECO:0000269|PubMed:11922622}.
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DR   EMBL; Z22179; CAA80171.2; -; Genomic_DNA.
DR   EMBL; Z22173; CAA80171.2; JOINED; Genomic_DNA.
DR   PIR; F88561; F88561.
DR   PIR; S40983; S40983.
DR   RefSeq; NP_499134.2; NM_066733.4.
DR   AlphaFoldDB; P34478; -.
DR   SMR; P34478; -.
DR   BioGRID; 41559; 5.
DR   IntAct; P34478; 3.
DR   STRING; 6239.F58A4.11; -.
DR   EPD; P34478; -.
DR   PaxDb; P34478; -.
DR   PeptideAtlas; P34478; -.
DR   PRIDE; P34478; -.
DR   EnsemblMetazoa; F58A4.11.1; F58A4.11.1; WBGene00001570.
DR   GeneID; 176364; -.
DR   KEGG; cel:CELE_F58A4.11; -.
DR   UCSC; F58A4.11; c. elegans.
DR   CTD; 176364; -.
DR   WormBase; F58A4.11; CE40812; WBGene00001570; gei-13.
DR   eggNOG; ENOG502SA89; Eukaryota.
DR   HOGENOM; CLU_398633_0_0_1; -.
DR   InParanoid; P34478; -.
DR   OMA; NQNTINM; -.
DR   OrthoDB; 913874at2759; -.
DR   PRO; PR:P34478; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00001570; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR003656; Znf_BED.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   SUPFAM; SSF57667; SSF57667; 2.
DR   PROSITE; PS50808; ZF_BED; 2.
PE   1: Evidence at protein level;
KW   Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger.
FT   CHAIN           1..691
FT                   /note="Gex-3-interacting protein 13"
FT                   /id="PRO_0000065375"
FT   ZN_FING         194..242
FT                   /note="BED-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   ZN_FING         424..473
FT                   /note="BED-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   REGION          18..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          171..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..50
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        57..97
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         212
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         215
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         230
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         235
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         443
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         446
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         461
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
FT   BINDING         466
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00027"
SQ   SEQUENCE   691 AA;  76740 MW;  8A2AF47028FE9007 CRC64;
     MTDCSSTLAA LLPTADFTAS LGNSDDHVDV SSFTTTSEST SPPYSSSEHH SPTDQRTETP
     TSDSGNASFS PENVATSFES SDRDASPDNL STSSAHLNDL QEKGVVVDEE LQRQLLRFHQ
     DFKESLMENN QNTINMMSAA FNQQLFKQTL ANLNTVTPQL PVNIPTGLPM PASPCTTAAS
     APSVESTPTK RKRQRRNPVW PYFDVIDGTA RCKQCLYSTK SVFSTNLKVH LRSHHRPDYE
     KVIMAEDALN LNALLLSGNT SKLFNVDANR KRMPPMTSSI LMTINKLANQ QQNGEENPLN
     AVLRQTIANN GLQQHLQNVQ TQLQAAQAAV QKQQQQQQQQ QIQQQQQQQQ QGAIPQFALN
     AANLAALNQL ARNQMQPTPP PVPQVSQDNI INTLNFPAHI KQEIMNAPHG TDANGVPQPK
     RRRLRRHPVW VYFKDLEDRM VGCTNCEFRT GSAFSTNLKM HLKAHHKDDY EKVLQLEEEM
     RLEEGCFGPG NKFKTELIDY IRGGGNVTTP PTPNSSSFPS TPKTPQLVQQ IISQSFARSQ
     SPNVIQNGEI KIKKECEDDM FSGLSSTDKL AALVGIAGQE VKKEEAMPAN FEEFRQRLLA
     NSSLSSFLGQ STAQPIAVDL NGSVIASETK SPCSSNEDDR KQERDKALAR LWADNETLLT
     NTHFREFVHC LAPEYEIPDV DILATSLVDQ Y