ID   GEMI7_SCHPO             Reviewed;          91 AA.
AC   G2TRR1;
DT   18-APR-2012, integrated into UniProtKB/Swiss-Prot.
DT   16-NOV-2011, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Gem-associated protein 7 homolog;
GN   Name=gem7 {ECO:0000303|PubMed:33754639};
GN   Synonyms=new17 {ECO:0000312|PomBase:SPBC32F12.16};
GN   ORFNames=SPBC32F12.16 {ECO:0000312|PomBase:SPBC32F12.16};
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=21270388; DOI=10.1534/genetics.110.123497;
RA   Bitton D.A., Wood V., Scutt P.J., Grallert A., Yates T., Smith D.L.,
RA   Hagan I.M., Miller C.J.;
RT   "Augmented annotation of the Schizosaccharomyces pombe genome reveals
RT   additional genes required for growth and viability.";
RL   Genetics 187:1207-1217(2011).
RN   [3]
RP   FUNCTION, IDENTIFICATION IN THE CORE SMN COMPLEX, INTERACTION WITH GEM6 AND
RP   GEM8, AND DISRUPTION PHENOTYPE.
RX   PubMed=33754639; DOI=10.1093/nar/gkab158;
RA   Veepaschit J., Viswanathan A., Bordonne R., Grimm C., Fischer U.;
RT   "Identification and structural analysis of the Schizosaccharomyces pombe
RT   SMN complex.";
RL   Nucleic Acids Res. 49:gkab158-gkab158(2021).
CC   -!- SUBUNIT: Part of the core SMN complex at least composed of smn1,
CC       yip11/gem2, gem6, gem7 and gem8 (PubMed:33754639). Interacts with gem6;
CC       the interaction is direct (PubMed:33754639). Interacts with gem8; the
CC       interaction is direct (PubMed:33754639). {ECO:0000269|PubMed:33754639}.
CC   -!- DISRUPTION PHENOTYPE: Inviable cell population.
CC       {ECO:0000269|PubMed:33754639}.
CC   -!- SIMILARITY: Belongs to the gemin-7 family. {ECO:0000305}.
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DR   EMBL; CU329671; CCD31374.1; -; Genomic_DNA.
DR   RefSeq; XP_004001722.1; XM_004001673.1.
DR   AlphaFoldDB; G2TRR1; -.
DR   SASBDB; G2TRR1; -.
DR   SMR; G2TRR1; -.
DR   STRING; 4896.SPBC32F12.16.1; -.
DR   MaxQB; G2TRR1; -.
DR   PaxDb; G2TRR1; -.
DR   EnsemblFungi; SPBC32F12.16.1; SPBC32F12.16.1:pep; SPBC32F12.16.
DR   PomBase; SPBC32F12.16; -.
DR   VEuPathDB; FungiDB:SPBC32F12.16; -.
DR   eggNOG; ENOG502T172; Eukaryota.
DR   HOGENOM; CLU_2428329_0_0_1; -.
DR   InParanoid; G2TRR1; -.
DR   OMA; SHLHTDW; -.
DR   PRO; PR:G2TRR1; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005634; C:nucleus; ISS:PomBase.
DR   GO; GO:0120114; C:Sm-like protein family complex; IBA:GO_Central.
DR   GO; GO:0032797; C:SMN complex; IDA:PomBase.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IMP:PomBase.
DR   InterPro; IPR020338; SMN_gemin7.
DR   PANTHER; PTHR14679; PTHR14679; 1.
DR   Pfam; PF11095; Gemin7; 1.
PE   2: Evidence at transcript level;
KW   mRNA processing; mRNA splicing; Reference proteome.
FT   CHAIN           1..91
FT                   /note="Gem-associated protein 7 homolog"
FT                   /id="PRO_0000416501"
SQ   SEQUENCE   91 AA;  10336 MW;  269EC2824A847305 CRC64;
     MAENNKKSTA YIQRMRTLKF YQKMASARIP ITVYLHDQRE VKAEFGAIDS SESKLAVSNL
     QTDWGVINRA VIRTGDVVGI EYNLVQEEGE L