GEML2_ARATH
ID GEML2_ARATH Reviewed; 233 AA.
AC Q9M122; Q6AWU5;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=GEM-like protein 2;
GN OrderedLocusNames=At4g01600; ORFNames=T15B16.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9M122-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9M122-2; Sequence=VSP_029570;
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to a competing donor splice
CC site. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the GEM family. {ECO:0000305}.
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DR EMBL; AL161492; CAB77730.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82050.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82051.1; -; Genomic_DNA.
DR EMBL; BT015153; AAT85749.1; -; mRNA.
DR EMBL; BT015662; AAU15161.1; -; mRNA.
DR PIR; G85020; G85020.
DR RefSeq; NP_001031570.1; NM_001036493.1. [Q9M122-2]
DR RefSeq; NP_192070.1; NM_116391.4. [Q9M122-1]
DR AlphaFoldDB; Q9M122; -.
DR PaxDb; Q9M122; -.
DR PRIDE; Q9M122; -.
DR ProteomicsDB; 224770; -. [Q9M122-1]
DR EnsemblPlants; AT4G01600.1; AT4G01600.1; AT4G01600. [Q9M122-1]
DR EnsemblPlants; AT4G01600.2; AT4G01600.2; AT4G01600. [Q9M122-2]
DR GeneID; 828085; -.
DR Gramene; AT4G01600.1; AT4G01600.1; AT4G01600. [Q9M122-1]
DR Gramene; AT4G01600.2; AT4G01600.2; AT4G01600. [Q9M122-2]
DR KEGG; ath:AT4G01600; -.
DR Araport; AT4G01600; -.
DR TAIR; locus:2133387; AT4G01600.
DR eggNOG; ENOG502R6FW; Eukaryota.
DR HOGENOM; CLU_063785_1_2_1; -.
DR InParanoid; Q9M122; -.
DR OMA; NPSANRW; -.
DR OrthoDB; 1201777at2759; -.
DR PhylomeDB; Q9M122; -.
DR PRO; PR:Q9M122; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9M122; baseline and differential.
DR Gene3D; 2.30.29.30; -; 1.
DR InterPro; IPR037848; GEM-like.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR31969; PTHR31969; 1.
DR Pfam; PF02893; GRAM; 1.
DR SMART; SM00568; GRAM; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..233
FT /note="GEM-like protein 2"
FT /id="PRO_0000311666"
FT DOMAIN 106..185
FT /note="GRAM"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 73..78
FT /note="GLKDHL -> V (in isoform 2)"
FT /evidence="ECO:0000303|Ref.3"
FT /id="VSP_029570"
SQ SEQUENCE 233 AA; 25913 MW; CD617C2A642FF17B CRC64;
MRPQYKDVND KLDSTAKHKT NSHGGRYDNP YVHITSPTSA SDKRSKDKVL EVLNRCGKKV
EDATRKAEAL VGGLKDHLKF SPSISDAAMA RLSQGTKMIV EGGPERVFQR EFGVLAVEKL
LDSFVCYIST TSGPVTGVIY ISNRRIAFCS DYAIRLPSSA GGNGVAAYYK VVMEWEKISS
ISSSTNVLKP SERYVHMVTR DGFEFWFMGF VSYIDAFNCL NKALLNSRCN HAM
